| Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2016: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2015: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2014: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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| Outline of Final Research Achievements |
Extrauterine growth restriction (EUGR) is associated with poor neurodevelopmental outcome in extremely preterm and/or very low birth weight infants. EUGR is associated with inadequate protein intake. Individualized human milk fortification has two approaches, adjustable human milk fortification and targeted human milk fortification. However, it remained unknown which is better fortification to prevent EUGR. Our study aim is to compare the effects on postnatal growth during NICU stay among these two approaches. There were no differences in SD scores for body weight, body length (BL) and head circumference (HC) at term equivalent age among two individualized fortification regimens. By individualized fortification, not only body weight and HC but also BL was equal to the reference fetus at term equivalent age. Higher protein intake by these two individualized fortification regimens may improve growth outcomes without linear growth depression in extremely preterm infants.
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