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The investigation regarding physiological effects of insulin resistance on treatment resistant mood disorder

Research Project

Project/Area Number 26461737
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Psychiatric science
Research InstitutionGunma University

Principal Investigator

Narita Kosuke  群馬大学, 医学部附属病院, 講師 (70345677)

Co-Investigator(Kenkyū-buntansha) 福田 正人  群馬大学, 大学院医学系研究科, 教授 (20221533)
Project Period (FY) 2014-04-01 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2016: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2015: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2014: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Keywords老年期精神障害 / 治療抵抗性気分障害 / 安静時脳MRI / 老年期気分障害 / インスリン抵抗性 / 脳MRI / 老年期うつ病
Outline of Final Research Achievements

The connectivity between Precuneus and Anterior Cingulate cortex in resting MRI were significantly associated with performance of risk taking in decision-making under risk condition in the elderlies. Then, resting MRI deta showed that power-law exponent obtained by fourier transformation was associated with reaction time.

Report

(4 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Research-status Report
  • 2014 Research-status Report
  • Research Products

    (6 results)

All 2016 2015 Other

All Int'l Joint Research (2 results) Journal Article (3 results) (of which Int'l Joint Research: 1 results,  Peer Reviewed: 2 results,  Open Access: 2 results,  Acknowledgement Compliant: 1 results) Remarks (1 results)

  • [Int'l Joint Research] University of Ottawa(Canada)

    • Related Report
      2016 Annual Research Report
  • [Int'l Joint Research] Ottawa University/McGill University(Canada)

    • Related Report
      2015 Research-status Report
  • [Journal Article] Gazefinder as a clinical supplementary tool for discriminating between autism spectrum disorder and typical development in male adolescents and adults.2016

    • Author(s)
      Fujioka T, Inohara K, Okamoto Y, Masuya Y, Ishitobi M, Saito DN, Jung M, Arai S, Matsumura Y, Fujisawa TX, Narita K, Suzuki K, Tsuchiya JK, Mori N, Katayama T, Sato M, Munesue T, Okazawa H, Tomoda A, Wada Y, Kosaka H.
    • Journal Title

      Molecular Autism

      Volume: 7 Issue: 1 Pages: 19-19

    • DOI

      10.1186/s13229-016-0083-y

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Blood Transcriptomic Markers in Patients with Late-Onset Major Depressive Disorder.2016

    • Author(s)
      Miyata S, Kurachi M, Okano Y, Sakurai N, Kobayashi A, Harada K, Yamagata H, Matsuo K, Takahashi K, Narita K, Fukuda M, Ishizaki Y, Mikuni M.
    • Journal Title

      PLoS One

      Volume: 11

    • Related Report
      2015 Research-status Report
  • [Journal Article] Relationship of γ-aminobutyric acid and glutamate+glutamine concentrations in the perigenual anterior cingulate cortex with performance of Cambridge Gambling Task.2015

    • Author(s)
      Fujihara K, Narita K, Suzuki Y, Takei Y, Suda M, Tagawa M, Ujita K, Sakai Y, Narumoto J, Near J, Fukuda M.
    • Journal Title

      Neuroimage

      Volume: 109 Pages: 102-8

    • DOI

      10.1016/j.neuroimage.2015.01.014

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Remarks] The Douglas Hospital Research Centre

    • URL

      http://douglas.research.mcgill.ca/jamie-near

    • Related Report
      2015 Research-status Report

URL: 

Published: 2014-04-04   Modified: 2018-03-22  

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