Clinicopathilogical study of frontotemporal lobar degeneretion
Project/Area Number |
26461752
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Research Category |
Grant-in-Aid for Scientific Research (C)
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Allocation Type | Multi-year Fund |
Section | 一般 |
Research Field |
Psychiatric science
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Research Institution | Yokohama City University |
Principal Investigator |
KATSUSE Omi 横浜市立大学, 医学部, 講師 (40420674)
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Project Period (FY) |
2014-04-01 – 2018-03-31
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Project Status |
Completed (Fiscal Year 2017)
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Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2016: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2015: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2014: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
|
Keywords | 認知症 / 神経病理 |
Outline of Final Research Achievements |
Frontotemporal lober degeneration (FTLD) presents various clinical symptoms and has several different pathological backgrounds. The autopsy brains of FTLD 72 cases was neuropathologically classified and the clinical symptoms were summarized.There were 29 cases of FTLD-tau, 32 cases of FTLD-TDP, and 10 cases of FTLD-FUS. In FTLD-FUS, basophilic inclusion body disease subtype was seen in 6 cases, three of which showed chorea, suggesting a link with this pathological background.
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Report
(5 results)
Research Products
(40 results)
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[Journal Article] Regional cerebral glucose metabolism in systemic lupus erythematosus patients with major depressive disorder.2017
Author(s)
Saito T, Tamura M, Chiba Y, Katsuse O, Suda A, Kamada A, Ikura T, Abe K, Ogawa M, Minegishi K, Yoshimi R, Kirino Y, Ihata A, Hirayasu Y.
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Journal Title
J Neurol Sci
Volume: 379
Pages: 127-130
DOI
Related Report
Peer Reviewed
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[Journal Article] Accumulated α-synuclein affects the progression of GM2 gangliosidoses.2016
Author(s)
Suzuki K, Yamaguchi A, Yamanaka S, Kanzaki S, Kawashima M, Togo T, Katsuse O, Koumitsu N, Aoki N, Iseki E, Kosaka K, Yamaguchi K, Hashimoto M, Aoki I, Hirayasu Y.
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Journal Title
Exp Neurol
Volume: 284
Pages: 38-49
DOI
Related Report
Peer Reviewed
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[Journal Article] Chorea as a clinical feature of the basophilic inclusion body disease subtype of fused-in-sarcoma-associated frontotemporal lobar degeneration.2016
Author(s)
Kawakami I, Kobayashi Z, Arai T, Yokota O, Nonaka T, Aoki N, Niizato K, Oshima K, Higashi S, Katsuse O, Hosokawa M, Hasegawa M, Akiyama H.
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Journal Title
Acta Neuropathol Commun.
Volume: 4
Pages: 36
DOI
Related Report
Peer Reviewed / Open Access
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[Journal Article] Brain FDG-PET reflecting clinical course of depression induced by systemic lupus erythematosus: Two case reports.2015
Author(s)
Saito T, Hama M, Chiba Y, Katsuse O, Kamada A, Ikura T, Minegishi K, Ihata A, Takahashi Y, Ishigatsubo Y, Hirayasu Y.
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Journal Title
J Neurol Sci.
Volume: 358
Pages: 464-466
DOI
Related Report
Peer Reviewed
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[Presentation] Relationship between the results of neuropsychological tests and the patterns of SPECT of mild cognitive impairment.2017
Author(s)
Kie Abe, Omi Katsuse, Hiroko Umezu, Yuhei Chiba, Takahiro Ikura, Naoya Aoki, Takashi Saeki, Kazumi Yamaguchi, Tomoko Nishio, Yoshio Hirayasu
Organizer
The 13th international conference on Alzheimer and Parkinson diseases 2017
Place of Presentation
Austria Centre Bruno-Kreisky-Platz, Wien, Austria
Year and Date
2017-03-28 – 2017-04-03
Related Report
Int'l Joint Research
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[Presentation] うつ病を伴う全身性エリテマトーデス患者の局所脳糖代謝(Regional Cerebral Glucose Metabolism in Systemic Lupus Erythematosus Patients with Major Depressive Disorder)2017
Author(s)
斎藤 知之, 田村 真麻, 千葉 悠平, 勝瀬 大海, 須田 顕, 鎌田 鮎子, 伊倉 崇浩, 服部 早紀, 阿部 紀絵, 尾川 松義, 峯岸 薫, 吉見 竜介, 井畑 淳, 平安 良雄
Organizer
第39回日本生物学的精神医学会・第47回日本神経精神薬理学会合同年会
Related Report
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[Presentation] Four cases of probable dementia with Lewy bodies with anti N-methyl-D-aspartic acid type receptor antibodies.2015
Author(s)
Chiba Y, Katsuse O, Fujishiro H, Ikura T, Toyohara N, Abe K, Takahashi Y, Hirayasu Y.
Organizer
International Dementia with Lewy Bodies Conference 2015,
Place of Presentation
Fort Lauderdale Marriott Harbor Resort & Spa, Fort Lauderdale, FL, USA.
Year and Date
2015-12-01 – 2015-12-04
Related Report
Int'l Joint Research
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[Presentation] Evaluation of titers of antibodies against peptides of subunit(NR1,NR2B) of glutamate receptor with enzyme-linked immunosorbent assay studies in psychiatric patients with anti-thyroid antibodies.2015
Author(s)
Ikura T, Katsuse O, Chiba Y, Takahashi Y, Fujishiro H, Takeno M, Hama M, Kamada A, Saito T, Hirayasu Y.
Organizer
IPA International Psychogeriatric Association International Congress
Place of Presentation
Estrel Berlin Hotel (Berlin,Germany)
Year and Date
2015-10-13 – 2015-10-16
Related Report
Int'l Joint Research
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[Presentation] Evaluation of Titers of Antibodies against Peptides of Glutamate Receptor in Psychiatric Patients with Anti-Thyroid,2015
Author(s)
Ikura T, Katsuse O, Chiba Y, Takahashi Y, Fujishiro H, Takeno M, Hama M, Kamada A, Saito T, Hirayasu Y.
Organizer
WPA REGIONAL CONGRESS OSAKA Japan 2015
Place of Presentation
Osaka International Convention Center (Osaka)
Year and Date
2015-06-04 – 2015-06-06
Related Report
Int'l Joint Research
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[Presentation] レビー小体型認知症剖検脳のMelanin-Concentrating Hormone (MCH)発現に関する神経病理学的検討.2014
Author(s)
近藤大三, 笠貫浩史, 藤城弘樹, 峯岸道子, 佐藤潔, 日野博昭, 勝瀬大海, 小阪憲司, 平安良雄, 新井平伊, 井関栄三.
Organizer
55回日本神経病理学会
Place of Presentation
学術総合センター(東京)
Year and Date
2014-06-05 – 2014-06-07
Related Report