Clinical value of F18 FDG PET in patients with connective tissue disease

• Project/Area Number: 26461795
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Radiation science
• Research Institution: Kagawa University
• Principal Investigator: Kawase Yoshiro 香川大学, 医学部, 協力研究員 (60169729)
• Co-Investigator(Kenkyū-buntansha): 山本 由佳 香川大学, 医学部, 准教授 (30335872) ; 奥田 花江 香川大学, 医学部, 助教 (10437692) ; 西山 佳宏 香川大学, 医学部, 教授 (50263900) ; 土橋 浩章 香川大学, 医学部, 講師 (50380176)
• Project Period (FY): 2014-04-01 – 2017-03-31
• Project Status: Completed (Fiscal Year 2016)
• Budget Amount: ¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000); Fiscal Year 2016: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000); Fiscal Year 2015: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000); Fiscal Year 2014: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
• Keywords: F-18 FDG / 炎症PET / 膠原病 / 治療効果判定 / 大動脈炎症候群 / 多発性筋炎 / 皮膚筋炎 / IgG4関連疾患 / 炎症PET検査

Outline of Final Research Achievements

Connective tissue diseases represent a heterogeneous group of immunologically mediated inflammatory disorders with a large variety of affected organs. 18F-fluorodeoxyglucose positron emission tomography (18F-FDG PET) is widely used in oncology but may also be valuable in patients with infections or inflammatory disease. Our experience demonstrates that 18F-FDG PET is a unique imaging technique for assessing the metabolic activity throughout the body in those with a connective tissue disease. Furthermore, 18F-FDG PET is also useful in the evaluation of disease activity.

Research Products

• [Presentation] IgG4関連疾患の治療前後におけるFDG PET/CTの検討 (2016)
  • Author(s): 奥田花江
  • Organizer: 第５６回日本核医学会学術総会
  • Place of Presentation: 名古屋市・名古屋国際会議場
  • Year and Date: 2016-11-03
• [Presentation] Volumetric parameters of whole-body FDG PET/CT for evaluating disease activity in patients with polymyositis/dermatomyositis (2016)
  • Author(s): Hanae Okuda
  • Organizer: Society of Nuclear Medicine and Molecular Imaging
  • Place of Presentation: San Diego, CA
  • Year and Date: 2016-06-11
  • Int'l Joint Research
• [Presentation] 多発性筋炎/皮膚筋炎におけるFDG PET/CTによる検討 (2015)
  • Author(s): 奥田花江
  • Organizer: 第５５回日本核医学会学術総会
  • Place of Presentation: 新宿区・ハイアットリージェンシー東京
  • Year and Date: 2015-11-05
• [Presentation] 大動脈炎症候群におけるFDG PETによる検討 (2014)
  • Author(s): 新井花江
  • Organizer: 第54回日本核医学会総会
  • Place of Presentation: 大阪市・大阪国際会議場
  • Year and Date: 2014-11-06 – 2014-11-08