The accuracy of new diagnostic modality for the diagnosis of colorectal tumors
| Project/Area Number |
26461815
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Radiation science
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| Research Institution | National Cancer Center Japan |
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Principal Investigator |
Kakugawa Yasuo 国立研究開発法人国立がん研究センター, 中央病院, 医長 (00537889)
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| Project Period (FY) |
2014-04-01 – 2017-03-31
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| Project Status |
Completed (Fiscal Year 2016)
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| Budget Amount *help |
¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
Fiscal Year 2016: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2015: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2014: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
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| Keywords | 大腸カプセル内視鏡 / 感度 / 平坦型腫瘍 / CTコロノグラフィー(大腸3D-CT) / 大腸腫瘍 / 大腸がん検診 |
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| Outline of Final Research Achievements |
We conducted a multicenter study to clarify the accuracy of colon capsule endoscopy as new diagnostic modality for the diagnosis of colorectal tumors (in particular, flat or depressed lesions). In this study, colon capsule endoscopy was shown to have 94% sensitivity (62/66). The relative sensitivity of colon capsule endoscopy compared to traditional total colonoscopy was 1.43 (165/115) in protruded lesion and 1.58 (82/52) in flat or depressed lesion. Then, we investigated the detection rate of colorectal lesions using dual camera devices equipped by colon capsule endoscopy in comparison with theological single camera devices. The dual camera increased the detection rate for flat or depressed lesion by a factor of 1.6-1.8 times higher when compared to a theological single camera. Our study revealed that colon capsule endoscopy has enough sensitivity for use in patients suspected of having flat or depressed lesions.
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Report
(4 results)
Research Products
(39 results)
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[Journal Article] Regional colorectal cancer screening program using colonoscopy on an island: a prospective Nii-jima study.2017
Author(s)
Hotta K, Matsuda T, Kakugawa Y, Ikematsu H, Kobayashi N, Kushima R, Hozawa A, Nakajima T, Sakamoto T, Mori M, Fujii T, Saito Y
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Journal Title
Japanese journal of clinical oncology
Volume: 47
Pages: 118-22
Related Report
Peer Reviewed / Open Access
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[Journal Article] Dual camera colon capsule endoscopy increases detection of colorectal lesions.2016
Author(s)
Takamaru H, Yamada M, Sakamoto T, Nakajima T, Saito Y, Kakugawa Y, Matsumoto M, Matsuda T, Ide D, Saito S, Gulati S, Tajiri H.
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Journal Title
Scandinavian journal of gastroenterology
Volume: 51
Pages: 1532-3
Related Report
Peer Reviewed / Open Access
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[Journal Article] 超高齢者の大腸癌スクリーニング2015
Author(s)
居軒 和也, 松田 尚久, 関口 正宇, 森 源喜, 高丸 博之, 山田 真善, 松本 美野里, 坂本 琢, 中島 健, 角川康夫, 斎藤 豊
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Journal Title
Intestine
Volume: 19
Pages: 73-78
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[Journal Article] Gene Expression Analysis Using a Highly Sensitive DNA Microarray for Colorectal Cancer Screening2014
Author(s)
Yoshikatsu Koga, Nobuyoshi Yamazaki, Satoko Takizawa, Junpei Kawauchi, Osamu Nomura, Seiichiro Yamamoto, Norio Saito, Yasuo Kakugawa, Yosuke Otake, Minori Matsumoto, Yasuhiro Matsumura
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Journal Title
Anticancer Research January
Volume: 34
Pages: 169-176
Related Report
Peer Reviewed / Open Access / Acknowledgement Compliant
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[Presentation] 家族性大腸腺腫症の十二指腸病変に対するバイポーラスネアを用いた内視鏡治療の短期成績.2016
Author(s)
居軒和也, 中島健, 野中哲, 高丸博之, 関口正宇, 山田真善, 阿部清一郎, 坂本琢, 鈴木晴久, 吉永繁高, 角川康夫, 松田尚久, 小田一郎, 斎藤豊.
Organizer
日本消化器内視鏡学会 関東支部会
Place of Presentation
シェーンバッハ・サボー（東京都千代田区平河町）
Year and Date
2016-06-11
Related Report
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[Presentation] Per Polyp Sensitivity of Colon Capsule Endoscopy According to Pathological Diagnosis2015
Author(s)
Yasuo Kakugawa, Shiro Oka, Shoichi Saito, Sadaharu Nouda, Kenji Watanabe, Naoki Ohmiya, Hiroyuki Aihara, Minori Matsumoto, Ikue Watari, Taiki Aoyama, Takanori Kuramoto, Kazuhide Higuchi, Hidemi Goto , Tetsuo Arakawa, Shinji Tanaka, Yutaka Saito, Hisao Tajiri
Organizer
UEGW
Place of Presentation
Spain
Year and Date
2015-10-27
Related Report
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