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The skeletal muscle conditioning for sports athletes by using multilateral evaluation system of magnetic resonance imaging

Research Project

Project/Area Number 26461818
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Radiation science
Research InstitutionUniversity of Tsukuba

Principal Investigator

Okamoto Yoshikazu  筑波大学, 医学医療系, 講師 (90420083)

Co-Investigator(Kenkyū-buntansha) 磯辺 智範  筑波大学, 医学医療系, 教授 (70383643)
宮川 俊平  筑波大学, 体育系, 教授 (10200130)
Project Period (FY) 2014-04-01 – 2018-03-31
Project Status Completed (Fiscal Year 2017)
Budget Amount *help
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2016: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2015: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2014: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Keywords骨格筋 / 拡散固有値 / ファイバートラクトグラフィー / 脂質代謝 / MRスペクトロスコピー / 筋血流 / IVIM / BOLD / MR angiography / 骨格筋MRI / 拡散テンソル / 拡散制限因子 / 細胞内脂肪 / 骨格筋血流 / 骨格筋硬度
Outline of Final Research Achievements

The main result of our study was to evaluate the microanatomy of the skeletal muscle using diffusion tensor imaging (DTI). We clarified the morphology of the skeletal muscle cell by using eigenvectors calculated by DTI. And also we clarified the existance of another diffusion restricting factors except for the membrane of the skeletal muscle cell. Moreover, we could succesfully generate the fiber tractography of the skeletal muscle by also using DTI. We also clarified the factors of failure of generating fiber tractography.
As for the lipid metaboolism of the skeletal muscle measured by MR spectroscopy, we clarified several factors including diabetis and subject's age could also affect the successful measurement of lipid metabolism of the skeletal muscle.

Report

(5 results)
  • 2017 Annual Research Report   Final Research Report ( PDF )
  • 2016 Research-status Report
  • 2015 Research-status Report
  • 2014 Research-status Report
  • Research Products

    (8 results)

All 2017 2016 2015 2014

All Journal Article (5 results) (of which Peer Reviewed: 5 results,  Open Access: 1 results,  Acknowledgement Compliant: 2 results) Presentation (3 results) (of which Int'l Joint Research: 1 results)

  • [Journal Article] Skeletal muscle mass to visceral fat area ratio is an important determinant affecting hepatic conditions of non-alcoholic fatty liver disease2017

    • Author(s)
      Shida Takashi、Akiyama Kentaro、Oh Sechang、Sawai Akemi、Isobe Tomonori、Okamoto Yoshikazu、Ishige Kazunori、Mizokami Yuji、Yamagata Kenji、Onizawa Kojiro、Tanaka Hironori、Iijima Hiroko、Shoda Junichi
    • Journal Title

      J Gastroenterol

      Volume: 53 Issue: 4 Pages: 535-547

    • DOI

      10.1007/s00535-017-1377-3

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] High-Intensity Aerobic Exercise Improves Both Hepatic Fat Content and Stiffness in Sedentary Obese Men with Nonalcoholic Fatty Liver Disease.2017

    • Author(s)
      Oh S, So R, Shida T, Matsuo T, Kim B, Akiyama K, Isobe T, Okamoto Y, Tanaka K, Shoda J.
    • Journal Title

      Sci Rep.

      Volume: 22 Pages: 7-7

    • NAID

      120007135013

    • Related Report
      2016 Research-status Report
    • Peer Reviewed
  • [Journal Article] Effect of biological factors on successful measurements with skeletal-muscle (1)H-MRS.2016

    • Author(s)
      Isobe T, Okamoto Y, Hirano Y, Ando H, Takada K, Sato E
    • Journal Title

      Ther Clin Risk Manag.

      Volume: 20 Pages: 1133-7

    • NAID

      120007129513

    • Related Report
      2016 Research-status Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Therapeutic effect of hybrid training of voluntary and electrical muscle contractions in middle-aged obese women with nonalcoholic fatty liver disease: a pilot trial.2015

    • Author(s)
      Oh S, Maruyama T, Eguchi K, Shida T, Arai E, Isobe T, Okamoto Y, Shoda J.
    • Journal Title

      Ther Clin Risk Manag.

      Volume: 4 Pages: 371-380

    • Related Report
      2015 Research-status Report
    • Peer Reviewed
  • [Journal Article] Changes in diffusion tensor imaging (DTI) eigenvalues of skeletal muscle due to hybrid exercise training.2014

    • Author(s)
      岡本嘉一
    • Journal Title

      Magnetic Resonance Imaging

      Volume: 32 Pages: 1297-1300

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Presentation] Is intramyocellular lipid a diffusion-restricting factor in skeletal muscle cells?2015

    • Author(s)
      Yoshikazu Okamoto
    • Organizer
      International Society for Magnetic Resonance in Medicine
    • Place of Presentation
      トロント
    • Year and Date
      2015-05-31 – 2015-06-03
    • Related Report
      2014 Research-status Report
  • [Presentation] Is intramyocellularlipid a diffusion-restricting factor in skeletal muscle cells?2015

    • Author(s)
      OkamotoY, Mori S, Isobe T, Hirano Y, Suzuki H, Minami M
    • Organizer
      International Society for Magnetic Resonance in Medicine
    • Place of Presentation
      トロント
    • Year and Date
      2015-05-30
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research
  • [Presentation] 筋肉トレーニングによる骨格筋細胞内拡散変化の追跡2014

    • Author(s)
      岡本嘉一
    • Organizer
      第42回日本磁気共鳴医学会大会
    • Place of Presentation
      京都
    • Year and Date
      2014-09-18 – 2014-09-20
    • Related Report
      2014 Research-status Report

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Published: 2014-04-04   Modified: 2019-03-29  

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