Evaluation of peripheral nerve impairment by diffusion tensor imaging

• Project/Area Number: 26461837
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Radiation science
• Research Institution: Toho University
• Principal Investigator: INAOKA Tsutomu 東邦大学, 医学部, 准教授 (00322892)
• Co-Investigator(Kenkyū-buntansha): 寺田 一志 東邦大学, 医学部, 教授 (90227520)
• Project Period (FY): 2014-04-01 – 2017-03-31
• Project Status: Completed (Fiscal Year 2016)
• Budget Amount: ¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000); Fiscal Year 2016: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000); Fiscal Year 2015: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000); Fiscal Year 2014: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
• Keywords: 末梢神経 / 正中神経 / MRI / 神経伝導速度測定 / 拡散テンソル画像 / 神経伝導速度 / ADC値 / FA値 / fiber tracking

Outline of Final Research Achievements

The purpose of this study was whether diffusion tensor maging was useful for the assessment of peripheral nerve impairment or not. By the experimental study using a peripheral nerve phantom, it was elucidated that changes of parameters of diffusion tensor imaging could influence the values from diffusion tensor imaging. Under fixed parameters of diffusion tensor imaging, diffusion tensor imaging for normal and abnormal median nerves was assessed. It was elucidated that the values from diffusion tensor imaging had a good correlation with those from the nerve conduction studies. In addition, there was a significant difference of the values from diffusion tensor imaging between normal and abnormal median nerves. Therefore, diffusion tensor imaging may be a useful tool for the assessment of peripheral nerve impairment.

Research Products

• [Presentation] 基礎から最新撮像技術を絡めた骨軟部画像診断～MRIを中心に～ (2017)
  • Author(s): 稲岡努
  • Organizer: 第70回千葉撮影技術研究会
  • Place of Presentation: 千葉大学（千葉県千葉市）
  • Year and Date: 2017-01-07
  • Invited
• [Presentation] 正中神経における拡散テンソルと神経伝達速度との相関性の検討 (2016)
  • Author(s): 酒井亮介，曽川将弘，中澤博行，戸澤光行，稲岡努，寺田一志，高橋修
  • Organizer: 第44回日本磁気共鳴医学会大会
  • Place of Presentation: 大宮ソニックシティ（埼玉県さいたま市）
  • Year and Date: 2016-09-09
• [Presentation] Comparison of 3D FSE Cube and 3D Fiesta-c sequences for image contrasts of the tissues on T2-weighted images in cervical spina MRI imaging at 3T (2016)
  • Author(s): Yumi Koizumi, Masaru Sonoda, Tsutomu Inaoka, Hitoshi Terada, and Hideki Nagatomo.
  • Organizer: ISMRM 24th annual meeting & exhibition
  • Place of Presentation: Singapore (Singapore)
  • Year and Date: 2016-05-12
  • Int'l Joint Research
• [Presentation] MR neurography (2015)
  • Author(s): Tsutomu Inaoka, Masayuki Odashima, Shusuke Kasuya, Rumiko Ishikawa, Tomoya Nakatsuka, Noriko Kitamura, Hitoshi Terada
  • Organizer: 42nd annual meeting and musculoskeletal imaging course: fundamentals to advanced concepts
  • Place of Presentation: Maui, Hawaii (USA)
  • Year and Date: 2015-09-29
  • Int'l Joint Research
• [Presentation] 頚部脊髄神経におけるvariable refocus flip angle 3D FSEの有用性 (2015)
  • Author(s): 小泉百未，園田優，稲岡努，永友秀樹
  • Organizer: 第43回日本磁気共鳴医学会大会
  • Place of Presentation: 東京ドームホテル，東京都
  • Year and Date: 2015-09-11
• [Presentation] Value of 3D FSE STIR images with blood-suppression pulse technique for the brachial plexus at 3T (2015)
  • Author(s): Tsutomu Inaoka, Masayuki Odashima, Mitsuyuki Tozawa, Hiroyuki Nakazawa, Masahiro Sogawa, Tomoya Nakatsuka, Rumiko Kasai, Hitoshi Terada
  • Organizer: ISMRM 23rd annual meeting & exhibition
  • Place of Presentation: Toronto (Canada)
  • Year and Date: 2015-06-01
  • Int'l Joint Research
• [Presentation] MR neurography (2015)
  • Author(s): Tsutomu Inaoka
  • Organizer: Imaging in Hawaii
  • Place of Presentation: Grand Hyatt Kauai (Kauai, Hawaii, USA)
  • Year and Date: 2015-03-24
  • Invited
• [Presentation] 拡散テンソル画像を用いた正中神経描出についての検討 (2015)
  • Author(s): 酒井亮介，曽川将宏，中澤博行，戸澤光行，稲岡努，寺田一志，岸雅彦，榊原隆次
  • Organizer: 第43回千葉MR研究会
  • Place of Presentation: 京葉銀行分化プラザ（千葉県千葉市）
  • Year and Date: 2015-02-28
• [Presentation] 正中神経を標的とした拡散テンソル画像撮像条件についての基礎的検討一報 (2014)
  • Author(s): 曽川将宏，戸澤光行，中澤博行，稲岡努，寺田一志
  • Organizer: 第42回日本磁気共鳴医学会
  • Place of Presentation: ホテルグランヴィア京都（京都府京都市）
  • Year and Date: 2014-09-19
• [Presentation] 正中神経を標的とした拡散テンソル画像撮像条件についての基礎的検討二報 (2014)
  • Author(s): 曽川将宏，戸澤光行，中澤博行，稲岡努，寺田一志
  • Organizer: 第42回日本磁気共鳴医学会
  • Place of Presentation: ホテルグランヴィア京都（京都府京都市）
  • Year and Date: 2014-09-19