A study of tumor diagnosis by whole-body dynamic imaging using positron emission tomography with continuous bed motion.
| Project/Area Number |
26461869
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Radiation science
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| Research Institution | Juntendo University (2016-2017)
Keio University (2014-2015) |
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Principal Investigator |
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| Project Period (FY) |
2014-04-01 – 2018-03-31
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| Project Status |
Completed (Fiscal Year 2017)
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| Budget Amount *help |
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2016: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2015: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2014: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
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| Keywords | ポジトロンCT / PET/CT / ダイナミック撮像 / FDG / 連続寝台移動 / 腫瘍診断 / 時間放射能曲線 / 生理的集積 / PET/CT装置 / FDG-PET / ダイナミック収集 / 悪性腫瘍 / SUV / 画像処理 |
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| Outline of Final Research Achievements |
Conventional PET image is usually obtained as “static” distribution of radiopharmaceuticals in the body. We newly developed “whole-body dynamic imaging (WBDI)” protocol using continuous bed motion PET scanner that enable us to analyze a change of distribution of radiopharmaceuticals according to time. The object is to discuss whether the method may useful for cancer diagnosis. At first, phantom study was performed to establish a feasible protocol to acquire WBDI, followed by studying for clinical application. In result, no significant difference was found for qualitative diagnosis using WBDI as long as image acquisition was started 1hour post injection, though it may effective for differentiate physiological uptake from pathological accumulation.
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Report
(5 results)
Research Products
(47 results)
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[Journal Article] Inter-evaluator heterogeneity of clinical diagnosis for locally advanced esophageal squamous cell carcinoma.2017
Author(s)
Hamamoto Y, Nojima M, Aoki Y, Suzuki T, Kawasaki K, Hirata K, Sukawa Y, Kasuga A, Kawakubo H, Takeuchi H, Murakami K, Takaishi H, Kanai T, Kitagawa Y.
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Journal Title
Esophagus
Volume: 14
Issue: 4
Pages: 324-332
DOI
NAID
Related Report
Peer Reviewed / Open Access
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[Journal Article] Limited Identification of Dual-time-point Positron Emission Tomography/Computed Tomography in Advanced Colorectal Neoplasms2017
Author(s)
Kashiwagi K, Nakazato Y, Arai M, Iwasaki E, Naganuma M, Inoue N, Iwao Y, Ogata H, Murakami K, Kanai T.
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Journal Title
Internal Medicine
Volume: 56
Issue: 11
Pages: 1287-1292
DOI
NAID
ISSN
0918-2918, 1349-7235
Related Report
Peer Reviewed / Open Access
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[Journal Article] Extremely Low Prevalence of Amyloid Positron Emission Tomography Positivity in Parkinson's Disease without Dementia.2017
Author(s)
Mashima K, Ito D, Kameyama M, Osada T, Tabuchi H, Nihei Y, Yoshizaki T, Noguchi E, Tanikawa M, Iizuka T, Date Y, Ogata Y, Nakahara T, Iwabuchi Y, Jinzaki M, Murakami K, Suzuki N
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Journal Title
Eur Neurol
Volume: 77
Issue: 5-6
Pages: 231-237
DOI
Related Report
Peer Reviewed / Int'l Joint Research
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[Journal Article] The efficacy of preoperative positron emission tomography-computed tomography(PET-CT) for detection of lymph node metastasis in cervical and endometrial cancer: clinical and pathological factors influencing it2014
Author(s)
Nogami Y, Banno K, Irie H, Iida M, Kisu I, Masugi Y, Tanaka K, Tominaga E, Okuda S, Murakami K, Aoki D.
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Journal Title
Japanese Journal of Clinical Oncology
Volume: 45
Issue: 1
Pages: 26-34
DOI
Related Report
Peer Reviewed / Open Access
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[Presentation] Equivalent image quality between continuous bed motion and step and shoot acquisition methods in positron emission tomography2017
Author(s)
Shota Takemoto, RT.1, Hideo Yamamoto, RT.1, Yuki Yamashiro, MD.1, Atsushi Nakanishi, MD.1, and Koji Murakami, MD, PhD.
Organizer
Society of nuclear medicine and molecular imaging
Related Report
Int'l Joint Research
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[Presentation] 骨・軟部腫瘍診断に対するFDG-PETの有用性の検討2016
Author(s)
西本 和正, 関田 哲也, 山口 さやか, 菊田 一貴, 須佐 美知郎, 堀内 圭輔, 矢部 啓夫, 村上 康二, 中村 雅也, 松本 守雄, 森岡 秀夫
Organizer
日本整形外科学会
Place of Presentation
パシフィコ横浜
Year and Date
2016-05-12
Related Report
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[Presentation] 大腸癌内視鏡治療後の追加腸切除における術前PET検査の有用性2016
Author(s)
田島 佑樹, 鶴田 雅士, 長谷川 博俊, 岡林 剛史, 茂田 浩平, 浅田 祐介, 杉浦 清昭, 鈴木 佳透, 中太 淳平, 村上 康二, 北川 雄光
Organizer
日本外科学会定期学術集会
Place of Presentation
大阪国際会議場
Year and Date
2016-04-14
Related Report
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[Presentation] 消化器癌のPET診断2014
Author(s)
村上康二
Organizer
第100回日本消化器病学会総会
Place of Presentation
東京国際フォーラム(東京都千代田区)
Year and Date
2014-04-26
Related Report
Invited
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