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Study of Modified Coaxial Needles Aimed at Expansion of Freezing Ranges.

Research Project

Project/Area Number 26461870
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Radiation science
Research InstitutionKeio University

Principal Investigator

Yashiro Hideki  慶應義塾大学, 医学部(信濃町), 共同研究員 (90327643)

Co-Investigator(Kenkyū-buntansha) 中塚 誠之  慶應義塾大学, 医学部(信濃町), 講師 (50188984)
井上 政則  慶應義塾大学, 医学部(信濃町), 助教 (30338157)
小黒 草太  慶應義塾大学, 医学部(信濃町), 助教 (50383716)
塚田 実郎  慶應義塾大学, 医学部(信濃町), 助教 (50573276)
須山 陽介  防衛医科大学校(医学教育部医学科進学課程及び専門課程、動物実験施設、共同利用研究施設、病院並びに防衛, 放射線医学, 助教 (00594607)
田村 全  慶應義塾大学, 医学部(信濃町), 助教 (50594602)
伊東 伸剛  慶應義塾大学, 医学部(信濃町), 助教 (00445248)
Project Period (FY) 2014-04-01 – 2018-03-31
Project Status Completed (Fiscal Year 2017)
Budget Amount *help
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2016: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2015: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2014: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Keywords画像下治療 / 凍結療法 / 焼灼療法 / インターベンショナルラジオロジー / 放射線医学 / インターベンショナルラジオロジー(IVR) / インターベンショナルラジオロジー(IVR)
Outline of Final Research Achievements

The purpose of this study is to introduce umbrella-shaped thermally conductive coaxial needles and directional thermally conductive coaxial needles and verify their effectiveness in order to obtain an expansion of freezing range during cryotherapy.
A stainless steel coaxial needle with six branches of 0.28 mm diameter was prepared as an umbrella-shaped thermally conductive coaxial needle, but it exhibited no practical function. A directional heat conducting coaxial needle consisting of side branches containing 0.8 mm diameter copper wires in 1.2 mm diameter Nitinol tubes with a shape memory property at its tip was prepared. It punctured lung and liver tissue safely during in vivo experiments and in the phantom experiment, the side branch showed a 33% expansion of the freezing range.

Report

(5 results)
  • 2017 Annual Research Report   Final Research Report ( PDF )
  • 2016 Research-status Report
  • 2015 Research-status Report
  • 2014 Research-status Report
  • Research Products

    (1 results)

All 2017

All Presentation (1 results) (of which Int'l Joint Research: 1 results)

  • [Presentation] Experimental works on thermal conduction during cryoablation2017

    • Author(s)
      S. Nakatsuka, H. Yashiro, M. Inoue, M. Tamura, S. Oguro, H. Torikai, J. Tsukada, M. Jinzaki
    • Organizer
      ECR
    • Place of Presentation
      Austria Center Vienna, Vienna, Austria
    • Year and Date
      2017-03-01
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research

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Published: 2014-04-04   Modified: 2019-03-29  

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