| Project/Area Number |
26461870
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Radiation science
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| Research Institution | Keio University |
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Principal Investigator |
Yashiro Hideki 慶應義塾大学, 医学部(信濃町), 共同研究員 (90327643)
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| Co-Investigator(Kenkyū-buntansha) |
中塚 誠之 慶應義塾大学, 医学部(信濃町), 講師 (50188984)
井上 政則 慶應義塾大学, 医学部(信濃町), 助教 (30338157)
小黒 草太 慶應義塾大学, 医学部(信濃町), 助教 (50383716)
塚田 実郎 慶應義塾大学, 医学部(信濃町), 助教 (50573276)
須山 陽介 防衛医科大学校(医学教育部医学科進学課程及び専門課程、動物実験施設、共同利用研究施設、病院並びに防衛, 放射線医学, 助教 (00594607)
田村 全 慶應義塾大学, 医学部(信濃町), 助教 (50594602)
伊東 伸剛 慶應義塾大学, 医学部(信濃町), 助教 (00445248)
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| Project Period (FY) |
2014-04-01 – 2018-03-31
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| Project Status |
Completed (Fiscal Year 2017)
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| Budget Amount *help |
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2016: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2015: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2014: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
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| Keywords | 画像下治療 / 凍結療法 / 焼灼療法 / インターベンショナルラジオロジー / 放射線医学 / インターベンショナルラジオロジー(IVR) / インターベンショナルラジオロジー（ＩＶＲ） |
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| Outline of Final Research Achievements |
The purpose of this study is to introduce umbrella-shaped thermally conductive coaxial needles and directional thermally conductive coaxial needles and verify their effectiveness in order to obtain an expansion of freezing range during cryotherapy.
A stainless steel coaxial needle with six branches of 0.28 mm diameter was prepared as an umbrella-shaped thermally conductive coaxial needle, but it exhibited no practical function. A directional heat conducting coaxial needle consisting of side branches containing 0.8 mm diameter copper wires in 1.2 mm diameter Nitinol tubes with a shape memory property at its tip was prepared. It punctured lung and liver tissue safely during in vivo experiments and in the phantom experiment, the side branch showed a 33% expansion of the freezing range.
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