| Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2016: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2015: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2014: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
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| Outline of Final Research Achievements |
We investigate the long-term clinical outcomes of cervical cancer patients treated with in-room computed tomography-based brachytherapy using Japanese standard radiotherapy schedule. The 5-year LC rate according to tumor size were 96%, 91%, and 94% for tumors <4 cm, tumors 4-6 cm, and tumors >6 cm, respectively. The proportions of patients with a high risk clinical target volume (HR-CTV) D90 of >60 Gy (EQD2), D2cc of the rectum of <75 Gy (EQD2), and D2cc of the bladder of <90 Gy (EQD2) were 90%, 99%, and 93%, respectively. There were no significant differences in the HR-CTV D90 among patients with different sized tumors. Then, along with the developing recommendations for contouring HR-CTV for cervical cancer, prospective evaluation in a multicenter setting has been on-going to confirm these findings.
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