| Project/Area Number |
26462085
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Cardiovascular surgery
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| Research Institution | Nagoya University |
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Principal Investigator |
Abe Tomonobu 名古屋大学, 医学部附属病院, 病院講師 (20378037)
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| Co-Investigator(Kenkyū-buntansha) |
安藤 昌彦 名古屋大学, 医学部附属病院, 准教授 (10322736)
碓氷 章彦 名古屋大学, 医学系研究科, 教授 (30283443)
大島 英揮 名古屋大学, 医学系研究科, 准教授 (40378188)
荒木 善盛 名古屋大学, 医学部附属病院, 病院講師 (70437010)
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| Project Period (FY) |
2014-04-01 – 2018-03-31
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| Project Status |
Completed (Fiscal Year 2017)
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| Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2016: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2015: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2014: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
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| Keywords | 人工弁 / 心臓弁膜症 / シミュレーション / メタアナリシス / 機械弁 / 出血 / 塞栓 / 弁膜症 / 長期成績 / 合併症 |
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| Outline of Final Research Achievements |
A meta-analysis of long term results of mechanical valve replacement was performed. We found that the incidence of valve relatred complication was different from western countries. The rate of bleeding complication was much less in Japan compared to western countries. We also performed microsimulation of deaths and complications following valve replacement using numbers obtained from the meta-analysis and found that best valve choice is very different between western countries and Japan. The paper, Influence of characteristics of Japanese patients on the long-term outcomes after aortic valve replacement: results of a microsimulation. received the best achievement award of Japanese society of thoracic surgery.
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