| Budget Amount *help |
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2016: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2015: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2014: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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| Outline of Final Research Achievements |
The microRNA is the small RNA molecules which does not encode protein. The object of this study is to examine whether microRNA is effective as biomarker of the lung cancer. I analyzed approximately 900 microRNA comprehensively. Then, I analyzed specific microRNA. As a result, I detected a decrease of five kinds of microRNA and five kinds of increase. Based on this result, I started examination about possibility as the biomarker whether the detection with the blood was possible. As a result of having searched the clinicopathologic factor which prescribed a variation rate of detection in blood, the result that the volume of tumor was related to was provided. By the gene analysis derived from a tumor in the blood, it was shown by the early lung cancer that became a target of the operation that the detection was difficult. I continue study about biomarker for lung cancer with microRNA.
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