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CBF and CSF flow using MRI

Research Project

Project/Area Number 26462220
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Neurosurgery
Research InstitutionTokai University

Principal Investigator

MATSUMAE Mitsunori  東海大学, 医学部, 教授 (20209604)

Co-Investigator(Kenkyū-buntansha) 厚見 秀樹  東海大学, 医学部, 准教授 (30307269)
反町 隆俊  東海大学, 医学部, 教授 (50534731)
黒田 輝  東海大学, 情報理工学部, 教授 (70205243)
Project Period (FY) 2014-04-01 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2016: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2015: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2014: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Keywordsレーザー / 温熱治療 / シミュレーションシステム / MRI / 温度 / 脳腫瘍 / シミュレーション / 脳脊髄液 / 流体力学 / 画像診断 / 位相画像 / 画像解析 / 神経生理学 / 水頭症 / 髄液
Outline of Final Research Achievements

Nobel of magnetic resonance imaging (MRI) has been determining to ensure not only images of the cerebrospinal fluid (CSF) motion but also physiological factors such as compliance, velocity, pressure gradient. Measurement of these physiological factors is determined ensure understanding to CSF environment. The authors determined to CSF motion in various part of CSF space, changes of the CSF environment with aging process, discriminate the patients with idiopathic normal pressure hydrocephalus (iNPH) from healthy elder volunteer.

Report

(4 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Research-status Report
  • 2014 Research-status Report
  • Research Products

    (10 results)

All 2017 2016 2015

All Journal Article (7 results) (of which Int'l Joint Research: 3 results,  Peer Reviewed: 4 results,  Open Access: 6 results,  Acknowledgement Compliant: 5 results) Presentation (3 results) (of which Invited: 1 results)

  • [Journal Article] Magnetic Resonance Imaging Technique for Visualization of Irregular Cerebrospinal Fluid Motion in the Ventricular System and Subarachnoid Space2017

    • Author(s)
      Horie T
    • Journal Title

      World Neurosurg

      Volume: 97 Pages: 523-531

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] 脳脊髄液運動の新知見2016

    • Author(s)
      松前光紀
    • Journal Title

      No Shinkei Geka

      Volume: 44 Pages: 909-924

    • Related Report
      2016 Annual Research Report
    • Open Access / Acknowledgement Compliant
  • [Journal Article] Research into the physiology of Cerebrospinal Fluid Reachse a New Horizon:Intimate Exchange between Cerebrospinal Fluid and Interstitial Fluid may Contribute to Maintenance of Homeostasis in the Central Nervous System2016

    • Author(s)
      Matsumae M
    • Journal Title

      Neurol Med Chirur (Tokyo)

      Volume: 56 Pages: 416-441

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Quantitative analysis of cerebrospinal fluid pressure gradients in healthy volunteers and patients with normal pressure hydrocephalus.2015

    • Author(s)
      Hayashi N, Matsumae M, Yatsushiro S, Hirayama A, Abdullah A, Kuroda K
    • Journal Title

      Neurol Med Chirur(Tokyo)

      Volume: 55 Pages: 657-662

    • NAID

      130005093138

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Visualization of pulsatile CSF motion around membrane-like structures with both 4D velocity mapping and time-slip technique.2015

    • Author(s)
      Hirayama A, Matsumae M, Yatsushiro S, Abdulla A, Atsumi H, Kuroda K
    • Journal Title

      Magn Reson Med Sci

      Volume: 14 Pages: 263-273

    • NAID

      130005109001

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Response. Regarding Bering's hypothesis on choroid plexus pulsatility.2015

    • Author(s)
      Matsumae M
    • Journal Title

      J Neurosurg

      Volume: 122 Pages: 480-481

    • Related Report
      2015 Research-status Report
    • Open Access / Int'l Joint Research
  • [Journal Article] 四次元速度画像に基づく髄液動態イメージングの臨床応用の現状と展望2015

    • Author(s)
      松前光紀, 厚見秀樹, 平山晃大, 林直一, 八ツ代諭, 梶原直, 船登美岬, 黒田輝
    • Journal Title

      INNERVISION

      Volume: 30 Pages: 19-21

    • Related Report
      2015 Research-status Report
  • [Presentation] 神経内視鏡の術前および術後において脳脊髄液運動を手早く可視化する撮像法2016

    • Author(s)
      滝沢 賢
    • Organizer
      第23回日本神経内視鏡学会
    • Place of Presentation
      東京ドームホテル (東京・文京区)
    • Year and Date
      2016-11-17
    • Related Report
      2016 Annual Research Report
  • [Presentation] MRI 4D Phase contrast 法により髄液運動の解析2016

    • Author(s)
      滝沢 賢
    • Organizer
      第17回日本正常圧水頭症学会
    • Place of Presentation
      山形テルサ (山形県・山形市)
    • Year and Date
      2016-03-19
    • Related Report
      2015 Research-status Report
  • [Presentation] 髄液の動きを可視化する2015

    • Author(s)
      松前光紀
    • Organizer
      第16回日本正常圧水頭症学会
    • Place of Presentation
      岡山コンベンションセンター
    • Year and Date
      2015-02-28
    • Related Report
      2014 Research-status Report
    • Invited

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Published: 2014-04-04   Modified: 2018-03-22  

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