| Budget Amount *help |
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2016: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2015: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2014: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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| Outline of Final Research Achievements |
We investigated the course of rat brain nerve activation after the peripheral nerve injury by functional MRI. The results of functional MRI showed the activated regions were contracted 3 and 6 weeks after the injury. In contrast, a significant increase in blood flow was seen 9 weeks after the injury. In addition, the brain regions in which the blood flow increased were stained in immunohistochemical staining with c-Fos. The present study could detect the sequential change of the rat brain after peripheral nerve injury. The result was consistent with c-Fos staining.
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