• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Establishment of optimal physical preventive intervention without using drugs and equipment for venous thromboembolism

Research Project

Project/Area Number 26462250
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Orthopaedic surgery
Research InstitutionKitasato University

Principal Investigator

Takahira Naonobu  北里大学, 医療衛生学部, 教授 (70236347)

Research Collaborator NAKANISHI Keisuke  
TSUDA Kouji  
Project Period (FY) 2014-04-01 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2016: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2015: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2014: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Keywords深部静脈血栓症 / 肺血栓塞栓症 / 静脈血栓塞栓症 / 静脈還流 / 呼吸 / 理学的予防法 / 足関節自動運動 / 姿勢 / 薬物的予防法 / 携帯型間欠的空気圧迫装置 / 下肢の不動肢位 / 被災地
Outline of Final Research Achievements

We examined the effect of isotonic or isometric exercise, which is the basis of active ankle joint movement (AAM), on the deep venous blood flow velocity or blood flow rate of the lower limbs for healthy adults. As a result, it was proved that it increases on a straight line.
In addition, we searched for proper timing by AAM and breathing style change according to posture change condition. As a result, the proper timing was clarified. We also compared the results between age differences. Moreover, as a new physical preventive method, we devised a combined use method of AAM and respiration method without using medicine and instruments, investigated and examined proper strength and frequency. As a result, it proved to be noninferior to the effect of improving deep venous blood flow of the lower limb using instruments.
In addition, we invented a " preventive device for deep venous thrombosis" which is an intermittent pneumatic compressor without power supply and filed a patent application.

Report

(4 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Research-status Report
  • 2014 Research-status Report
  • Research Products

    (47 results)

All 2017 2016 2015 2014

All Journal Article (22 results) (of which Int'l Joint Research: 16 results,  Peer Reviewed: 18 results,  Acknowledgement Compliant: 2 results,  Open Access: 7 results) Presentation (22 results) (of which Int'l Joint Research: 4 results,  Invited: 5 results) Book (2 results) Patent(Industrial Property Rights) (1 results)

  • [Journal Article] The cytokine expression in synovial membrane and the relationship with pain and pathological findings at hip arthroscopy2017

    • Author(s)
      Fukushima K, Inoue G, Fujimaki H, Uchida K, Miyagi M, Nagura N, Uchiyama K, Takahira N, Takaso M.
    • Journal Title

      J Exp Orthop

      Volume: 4(1):12 Issue: 1

    • DOI

      10.1186/s40634-017-0086-4

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Pre-operative simulation of periacetabular osteotomy via a three-dimensional model constructed from salt.2017

    • Author(s)
      Fukushima K, Takahira N, Uchiyama K, Moriya M, Takaso M.
    • Journal Title

      SICOT J

      Volume: 3:14 Pages: 14-14

    • DOI

      10.1051/sicotj/2016051

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Clinical results of arthroscopic surgery in patients over 50 years of age-what viability does it have as a joint preservative surgery?2017

    • Author(s)
      Moriya M, Fukushima K, Uchiyama K, Takahira N, Yamamoto T, Minegishi Y, Takaso M.
    • Journal Title

      J Orthop Surg Res

      Volume: 6;12(1):2 Issue: 1

    • DOI

      10.1186/s13018-016-0504-9

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Effects of intermittent pneumatic compression of the thigh on blood flow velocity in the femoral and popliteal veins: developing a new physical prophylaxis for deep vein thrombosis in patients with plaster-cast immobilization of the leg2016

    • Author(s)
      Nakanishi K, Takahira N, Sakamoto M, Yamaoka-Tojo M, Katagiri M, Kitagawa J.
    • Journal Title

      J Thromb Thrombolysis

      Volume: 42(4) Issue: 4 Pages: 579-584

    • DOI

      10.1007/s11239-016-1403-y

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] The incidence of deep vein thrombosis (DVT) during hip arthroscopic surgery2016

    • Author(s)
      Fukushima K, Takahira N, Uchiyama K, Moriya M, Minato T, Takaso M.
    • Journal Title

      Arch Orthop Trauma Surg

      Volume: 136(10) Issue: 10 Pages: 1431-1435

    • DOI

      10.1007/s00402-016-2508-7

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Prevalence of radiological findings related to femoroacetabular impingement in professional baseball players in Japan.2016

    • Author(s)
      Fukushima K, Takahira N, Imai S, Yamazaki T, Kenmoku T, Uchiyama K, Takaso M.
    • Journal Title

      J Orthop Sci

      Volume: 21(6) Issue: 6 Pages: 821-825

    • DOI

      10.1016/j.jos.2016.07.003

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Ankle fracture as a complication of hip arthroscopy: A case report2016

    • Author(s)
      Fukushima K, Takahira N, Uchiyama K, Moriya M, Yamamoto T, Takaso M.
    • Journal Title

      J Orthop Sci

      Volume: 4 Issue: 2 Pages: 420-423

    • DOI

      10.1016/j.jos.2016.06.007

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Spinal correction of scoliosis in Jeune syndrome: a report of two cases2016

    • Author(s)
      Saito W, Inoue G, Imura T, Nakazawa T, Miyagi M, Namba T, Shirasawa E, Takahira N, Takaso M.
    • Journal Title

      Scoliosis Spinal Disord

      Volume: 2;11:7 Issue: 1

    • DOI

      10.1186/s13013-016-0069-8

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Remarkable regression of a giant cell tumor of the cervical spine treated conservatively with denosumab: A case report2016

    • Author(s)
      Nakazawa T, Inoue G, Imura T, Miyagi M, Saito W, Namba T, Shirasawa E, Uchida K, Takahira N, Takaso M.
    • Journal Title

      Int J Surg Case Rep.

      Volume: 24 Pages: 22-25

    • DOI

      10.1016/j.ijscr.2016.05.008

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Spinal Epidural Hematoma after Thoracolumbar Posterior Fusion Surgery without Decompression for Thoracic Vertebral Fracture.2016

    • Author(s)
      Minato T, Miyagi M, Saito W, Shoji S, Nakazawa T, Inoue G, Imura T, Minehara H, Matsuura T, Kawamura T, Namba T, Takahira N, Takaso M.
    • Journal Title

      Case Rep Orthop

      Volume: - Pages: 6295817-6295817

    • DOI

      10.1155/2016/6295817

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Comparison of locomotion including postoperative trunk deflection between direct lateral and anterolateral approaches in supine total hip arthroplasty2016

    • Author(s)
      Nishimura M, Takahira N, Fukushima K, Uchiyama K, Moriya M, Yamamoto T
    • Journal Title

      J Arthroplasty

      Volume: 9 Issue: 7 Pages: 1-6

    • DOI

      10.1016/j.arth.2015.12.043

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Early gait analysis after curved periacetabular osteotomy for acetabular dysplasia2015

    • Author(s)
      Nishimura M, Takahira N, Fukushiuma K, Yamamoto T, Moriya M, Uchiyama K
    • Journal Title

      Orthopedic Research and Reviews

      Volume: 7 Pages: 1-8

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Reduction in the soles of graduated compression stockings prevents falls without reducing the preventive effect for venous stasis2015

    • Author(s)
      Kuroiwa M, Takahira N, Ujihashi Y, Miida K, Arai Y, Kawatani H
    • Journal Title

      Thromb Res

      Volume: 135(5) Issue: 5 Pages: 877-81

    • DOI

      10.1016/j.thromres.2015.02.028

    • Related Report
      2015 Research-status Report 2014 Research-status Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] わが国における静脈血栓塞栓症予防における携帯型間欠的空気圧迫装置の臨床応用に向けた有用性の検討2015

    • Author(s)
      志田真澄,高平尚伸,中西啓祐,坂本美喜
    • Journal Title

      関節外科

      Volume: 34(3) Pages: 83-89

    • Related Report
      2015 Research-status Report 2014 Research-status Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Effectiveness of deep peroneal nerve block for the management of lumbar disease with leg cramps2015

    • Author(s)
      Imura T, Inoue G, Nakazawa T, Ueno M, Saito W, Uchida K, Adachi K, Takahira N, Takaso M
    • Journal Title

      J Spine Res

      Volume: 6 Pages: 119-124

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Loxoprofen sodium and celecoxib for postoperative pain in patients after spinal surgery: a randomized comparative study2015

    • Author(s)
      Sekiguchi H, Inoue G, Nakazawa T, Imura T, Saito W, Uchida K, Miyagi M, Takahira N, Takaso M
    • Journal Title

      J Orthop Sci

      Volume: 20(4) Pages: 617-623

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Long-term warfarin therapy and biomarkers for osteoporosis and atherosclerosis2015

    • Author(s)
      Namba S, Yamaoka-Tojo M, Hashikata T, Ikeda Y, Kitasato L, Hashimoto T, Kameda R, Shimohama T, Tojo T, Takahira N, Masuda T, Ako J
    • Journal Title

      BBA Clin

      Volume: 12(4) Pages: 76-80

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] 抗凝固薬. 特集「最新整形外科医が知っておきたい薬の使い方」2015

    • Author(s)
      高平尚伸,冨沢淳
    • Journal Title

      関節外科

      Volume: 34 Pages: 244-251

    • Related Report
      2015 Research-status Report
  • [Journal Article] 下肢深部静脈に対する弾性ストッキングの血流増加効果2014

    • Author(s)
      黒岩政之,宇治橋善勝,高平尚伸,栗田かほる,横田友希,長田真由美,鈴木政子,見井田和正,川谷弘子,荒井有美
    • Journal Title

      静脈学

      Volume: 25 Pages: 326-331

    • NAID

      130004680269

    • Related Report
      2014 Research-status Report
    • Peer Reviewed
  • [Journal Article] 人工関節置換術後における静脈血栓塞栓症予防法の工夫-抗凝固薬のSwitch法-2014

    • Author(s)
      高平尚伸,河村直,内山勝文,福島健介,森谷光俊,山本豪明,峯岸洋次郎, 関口裕之,相川淳,岩瀬大,東山礼治,高相晶士
    • Journal Title

      日本人工関節学会雑誌

      Volume: 44 Pages: 31-32

    • Related Report
      2014 Research-status Report
  • [Journal Article] 【四肢の循環不全と理学療法】 深部静脈血栓症に対する理学療法2014

    • Author(s)
      奥津千詩,坂本美喜,高平尚伸
    • Journal Title

      理学療法

      Volume: 31(10) Pages: 1006-1013

    • Related Report
      2014 Research-status Report
  • [Journal Article] リスクマネージメント 院内での薬剤師の活動 術後の静脈血栓塞栓症予防に用いる抗凝固薬のBleeding Risk Score表の構築2014

    • Author(s)
      冨沢淳,黒岩政之,高平尚伸,厚田幸一郎
    • Journal Title

      医薬品ジャーナル

      Volume: 50(9) Pages: 2302-2307

    • Related Report
      2014 Research-status Report
  • [Presentation] 人工関節周術期DVT/VTEに関する考え方2017

    • Author(s)
      高平尚伸,福島健介,内山勝文,山本豪明,森谷光俊,峯岸洋次郎,相川淳,東山礼治,岩瀬大,南谷淳,河村直,高相晶士
    • Organizer
      第47回人工関節学会
    • Place of Presentation
      沖縄コンベンションセンター(沖縄県宜野湾市)
    • Year and Date
      2017-02-24
    • Related Report
      2016 Annual Research Report
  • [Presentation] 患者のリスクレベルに応じたVTEの予防対策2017

    • Author(s)
      高平尚伸
    • Organizer
      第2回南大阪整形外科冬季セミナー
    • Place of Presentation
      ホテル日航大阪(大阪府大阪市)
    • Year and Date
      2017-01-12
    • Related Report
      2016 Annual Research Report
    • Invited
  • [Presentation] An exercise resistance band enhances the active ankle exercise-induced increase in lower extremity venous blood flow2016

    • Author(s)
      Tsuda K, Takahira N, Sakamoto M, Ejiri M
    • Organizer
      37th SICOT Orthopaedic World Congress
    • Place of Presentation
      Rome Marriott Park Hotel & Convention Centre (Rome, Italy)
    • Year and Date
      2016-09-08
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] VTE 予防策としての理学的予防法2016

    • Author(s)
      高平尚伸
    • Organizer
      第2回北里VTEフォーラム
    • Place of Presentation
      北里大学病院 (相模原市南区)
    • Year and Date
      2016-07-05
    • Related Report
      2016 Annual Research Report
    • Invited
  • [Presentation] 運動用ゴムバンドによる抵抗はAAE時の下肢静脈血流をより促進させる2016

    • Author(s)
      津田晃司,高平尚伸
    • Organizer
      第36回日本静脈学会
    • Place of Presentation
      ホテルナクアシティ弘前(青森都弘前市)
    • Year and Date
      2016-06-23
    • Related Report
      2016 Annual Research Report
  • [Presentation] ギプス固定者に対するDVT予防法としての深呼吸法の検討2016

    • Author(s)
      津田晃司, 坂本美喜, 東條美奈子, 片桐真人, 高平尚伸
    • Organizer
      第53回日本リハビリテーション医学会
    • Place of Presentation
      国立京都国際会館 グランドプリンスホテル京都(京都府京都市)
    • Year and Date
      2016-06-09
    • Related Report
      2016 Annual Research Report
  • [Presentation] 人工股関節置換術の最新手術手技と周術期管理2016

    • Author(s)
      高平尚伸
    • Organizer
      第3回圏央道整形外科研究会
    • Place of Presentation
      町田,東京,ホテル ザ・エルシィ町田
    • Year and Date
      2016-03-17
    • Related Report
      2015 Research-status Report
    • Invited
  • [Presentation] 患者のリスクレベルに応じた静脈血栓塞栓症の予防対策2016

    • Author(s)
      高平尚伸
    • Organizer
      静脈血栓症予防治療講演会
    • Place of Presentation
      名護,沖縄,沖縄県立北部病院
    • Year and Date
      2016-03-14
    • Related Report
      2015 Research-status Report
    • Invited
  • [Presentation] 股関節鏡視下手術における深部静脈血栓症の発生率2015

    • Author(s)
      福島健介,高平尚伸,湊剛樹,内山勝文,森谷光俊,山本豪明,峯岸洋次郎,高相晶士
    • Organizer
      第43回関東股関節懇話会
    • Place of Presentation
      千代田区, 東京,日本工業倶楽部会館
    • Year and Date
      2015-09-26
    • Related Report
      2015 Research-status Report
  • [Presentation] High-intensity isometric contraction of the triceps surae increases lower extremity venous blood flow velocity2015

    • Author(s)
      Tsuda K, Takahira N, Shinkai A, Kaji K, Sakamoto M
    • Organizer
      36th SICOT
    • Place of Presentation
      GuangZhou, 中国, Guangzhou Baiyun International Convention Center
    • Year and Date
      2015-09-17
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research
  • [Presentation] High-intensity isotonic contraction of the triceps surae increases lower extremity venous blood flow velocity2015

    • Author(s)
      Tsuda K, Takahira N, Shinkai A, Kaji K, Sakamoto M
    • Organizer
      36th SICOT
    • Place of Presentation
      GuangZhou, 中国, Guangzhou Baiyun International Convention Center
    • Year and Date
      2015-09-17
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research
  • [Presentation] 股関節鏡視下手術における深部静脈血栓症の発生率と危険因子2015

    • Author(s)
      福島健介,高平尚伸,湊剛樹,内山勝文,森谷光俊,山本豪明,峯岸洋次郎,高相晶士
    • Organizer
      第7回日本関節鏡膝スポーツ整形外科学会(JOSKAS 2015)
    • Place of Presentation
      札幌, 北海道,札幌市産業振興センター
    • Year and Date
      2015-06-18
    • Related Report
      2015 Research-status Report
  • [Presentation] 多発外傷も含めた下肢骨盤骨折における当院での深部静脈血栓症の発生頻度の検討2015

    • Author(s)
      河村直,高平尚伸,峰原宏昌,鈴木卓,松浦晃正,中脇充章,難波孝徳,白澤栄樹,庄司真太郎,浅利靖,高相晶士
    • Organizer
      第29回日本外傷学会
    • Place of Presentation
      札幌, 北海道,札幌コンベンションセンター
    • Year and Date
      2015-06-11
    • Related Report
      2015 Research-status Report
  • [Presentation] Deep Breathing as Prophylaxis for Deep Vein Thrombosis: Focusing on Airflow Velocity2015

    • Author(s)
      Tsuda K, Sakamoto M, Yamaoka-Tojo M, Katagiri M, Kitagawa J, Takahira N
    • Organizer
      WCPT (world confederation for physical therapy: 世界理学療法学会)
    • Place of Presentation
      Suntec Singapore Convention and Exhibition Centre, Singapore
    • Year and Date
      2015-05-01 – 2015-05-04
    • Related Report
      2014 Research-status Report
  • [Presentation] Deep breathing as prophylaxis for deep vein thrombosis: Focusing on airflow velocity2015

    • Author(s)
      Tsuda, K, Sakamoto, M, Yamaoka-Tojo, M, Katagiri, M, Kitagawa, J, Takahira, N
    • Organizer
      WCPT (World Confederation for Physical Therapy)
    • Place of Presentation
      Singapore,Singapore, Suntec Singapore International Convention & Exhibition Centre
    • Year and Date
      2015-05-01
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research
  • [Presentation] Development of a new physical prophylaxis for deep vein thrombosis in patients with plaster-cast immobilization of the leg : Effects of intermittent pneumatic compression on the thigh on blood flow velocity in the femoral and popliteal veins2014

    • Author(s)
      Nakanishi K, Sakamoto M, Tojo M, Katagiri M, Kitagawa J, Takahira N
    • Organizer
      SICOT(国際整形災害外科学会)
    • Place of Presentation
      SulAmerica Convention Centre(Rio de Janeiro, Brasil)
    • Year and Date
      2014-11-19 – 2014-11-22
    • Related Report
      2014 Research-status Report
  • [Presentation] Development of a new physical prophylaxis for deep vein thrombosis in patients with plaster-cast immobilization of the leg :Effects of forced deep breathing on blood flow velocity in the femoral vein2014

    • Author(s)
      Nakanishi K, Sakamoto M, Tojo M, Katagiri M, Kitagawa J, Takahira N
    • Organizer
      SICOT(国際整形災害外科学会)
    • Place of Presentation
      SulAmerica Convention Centre(Rio de Janeiro, Brasil)
    • Year and Date
      2014-11-19 – 2014-11-22
    • Related Report
      2014 Research-status Report
  • [Presentation] 整形外科領域における手術・検査前中止薬に対する外来薬局薬剤師の関わり2014

    • Author(s)
      赤嶺聡彦,宇野真理子,竹下さおり,小林由佳,細井祥生,山村昌紀,平塚公己,太田智博,横山浩子,川野千尋,飛田夕紀,石塚愛,本間雅士,小原美江,高平尚伸,黒山政一
    • Organizer
      医療薬学会年会
    • Place of Presentation
      名古屋国際会議場(愛知県名古屋市)
    • Year and Date
      2014-09-27
    • Related Report
      2014 Research-status Report
  • [Presentation] 静脈血栓塞栓症予防における携帯型間欠的空気圧迫装置の有用性の検討2014

    • Author(s)
      高平尚伸,志田真澄,中西啓祐,坂本美喜,内山勝文,福島健介,山本豪明,森谷光俊
    • Organizer
      Hip forum
    • Place of Presentation
      The Luigans(福岡県福岡市)
    • Year and Date
      2014-07-25
    • Related Report
      2014 Research-status Report
  • [Presentation] トレンカ型弾性ストッキングにおける下肢静脈血流増加効果の検討2014

    • Author(s)
      宇治橋善勝,黒岩政之,高平尚伸,鈴木政子,川谷弘子,荒井有美,棟方伸一,狩野有作
    • Organizer
      日本超音波検査学会
    • Place of Presentation
      名古屋国際会議場(愛知県名古屋市)
    • Year and Date
      2014-06-13
    • Related Report
      2014 Research-status Report
  • [Presentation] 患者のリスクレベルに応じた静脈血栓塞栓症の予防対策2014

    • Author(s)
      高平尚伸
    • Organizer
      三重整形外科静脈血栓塞栓症研究会
    • Place of Presentation
      三重県立総合文化センター(三重県津市)
    • Year and Date
      2014-05-29
    • Related Report
      2014 Research-status Report
    • Invited
  • [Presentation] 足関節自動運動の下肢深部静脈血流増加効果の持続的有効性と下腿筋ポンプ作用に関わる因子の検討―若年者と高齢者による層別ランダム化比較試験―2014

    • Author(s)
      芦原光明,高平尚伸,太附広明
    • Organizer
      日本静脈学会
    • Place of Presentation
      万国津梁館(沖縄県名護市)
    • Year and Date
      2014-04-18
    • Related Report
      2014 Research-status Report
  • [Book] 体操療法オールブック(静脈血栓塞栓症のための体操)2016

    • Author(s)
      中西啓祐,高平尚伸
    • Total Pages
      8
    • Publisher
      メジカルビュー
    • Related Report
      2015 Research-status Report
  • [Book] この症状を見逃さない.戦略的循環器疾患の診かた2014

    • Author(s)
      河村直,高平尚伸
    • Total Pages
      272
    • Publisher
      南山堂
    • Related Report
      2014 Research-status Report
  • [Patent(Industrial Property Rights)] 深部静脈血栓予防具2015

    • Inventor(s)
      高平尚伸
    • Industrial Property Rights Holder
      学校法人北里研究所
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2015-046252
    • Filing Date
      2015-03-09
    • Related Report
      2014 Research-status Report

URL: 

Published: 2014-04-04   Modified: 2018-03-22  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi