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Development of treatment for the osteoarthritis with chondroprogenitor cells

Research Project

Project/Area Number 26462297
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Orthopaedic surgery
Research InstitutionShimane University

Principal Investigator

Uchio Yuji  島根大学, 医学部, 教授 (20223547)

Co-Investigator(Kenkyū-buntansha) 熊橋 伸之  島根大学, 医学部, 講師 (00457178)
桑田 卓  島根大学, 医学部, 助教 (80509000)
Project Period (FY) 2014-04-01 – 2018-03-31
Project Status Completed (Fiscal Year 2017)
Budget Amount *help
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2016: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2015: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2014: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Keywords変形性関節症 / 軟骨前駆細胞
Outline of Final Research Achievements

A Japanese white person rabbit deformation properties knee arthropathy model is made, intra-articular injection does a cartilage leading cell, and, arthropathy, the value of the change and the organization scholarly value were performed. Prescription in the synovial cavity was being performed and passage was being observed, but without doing immunosuppressed even if 1 month was passed after prescription, there was no clear adverse event. You suppose to indicate the effect higher than the leaf system stem cell while treatment by an injection in the synovial cavity of REC to cartilage damage is reported in the past. It's expected to inspect about restoration by a hyaline cartilage, progress prevention of deformation properties arthropathy and reduction in sharp pain to cartilage damage.

Report

(5 results)
  • 2017 Annual Research Report   Final Research Report ( PDF )
  • 2016 Research-status Report
  • 2015 Research-status Report
  • 2014 Research-status Report
  • Research Products

    (10 results)

All 2018 2017 2016

All Presentation (9 results) (of which Invited: 7 results) Book (1 results)

  • [Presentation] 変形性関節症に対する保存療法の有効性と課題2018

    • Author(s)
      内尾祐司:
    • Organizer
      第130回中部日本整形外科災害外科学会学術集会.
    • Related Report
      2017 Annual Research Report
  • [Presentation] 変形性膝関節症に対する保存療法の有効性と課題.2017

    • Author(s)
      内尾祐司
    • Organizer
      第133回西日本整形・災害外科学会学術集会.
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] 膝関節痛を科学する。-病態解明と治療戦略―2017

    • Author(s)
      内尾祐司:
    • Organizer
      第15回北海道関節疾患研究会
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] 変形性関節症治療の新たな選択肢~患者から求められる治療とは~.2017

    • Author(s)
      内尾祐司:
    • Organizer
      神奈川西湖地区整形外科講演会秋季講演会.
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] 変形性関節症に対する保存療法の有効性と課題2017

    • Author(s)
      内尾祐司:
    • Organizer
      第45回日本関節病学会.
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] 早期変形性膝関節症の臨床的特徴と診断(シンポジウム).2016

    • Author(s)
      内尾祐司
    • Organizer
      第44回日本関節病学会
    • Place of Presentation
      別府
    • Year and Date
      2016-11-11
    • Related Report
      2016 Research-status Report
  • [Presentation] 変形性膝関節症の薬物療法の有効性と課題2016

    • Author(s)
      内尾祐司
    • Organizer
      第31回日本整形外科学会基礎学術集会
    • Place of Presentation
      福岡
    • Year and Date
      2016-10-13
    • Related Report
      2016 Research-status Report
    • Invited
  • [Presentation] スポーツにともなう膝関節軟骨傷害の治療戦略―症状緩和と関節症予防―2016

    • Author(s)
      内尾祐司
    • Organizer
      第42回日本整形外科スポーツ医学会学術集会.
    • Place of Presentation
      札幌
    • Year and Date
      2016-09-16
    • Related Report
      2016 Research-status Report
    • Invited
  • [Presentation] ロコモの原因疾患としての変形性膝関節症の治療戦略2016

    • Author(s)
      内尾祐司
    • Organizer
      第29回日本臨床整形外科学会学術集会
    • Place of Presentation
      札幌
    • Year and Date
      2016-07-16
    • Related Report
      2016 Research-status Report
    • Invited
  • [Book] リウマチ病学テキスト改訂第2版2016

    • Author(s)
      内尾祐司
    • Total Pages
      624
    • Publisher
      診断と治療社
    • Related Report
      2016 Research-status Report

URL: 

Published: 2014-04-04   Modified: 2019-03-29  

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