Establishment of the double-contrast agent -an effort to detect the rabbit knee cartilage degeneration in the early stage-
Project/Area Number |
26462311
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Research Category |
Grant-in-Aid for Scientific Research (C)
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Allocation Type | Multi-year Fund |
Section | 一般 |
Research Field |
Orthopaedic surgery
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Research Institution | Kyoto Prefectural University of Medicine |
Principal Investigator |
Ikoma Kazuya 京都府立医科大学, 医学(系)研究科(研究院), 講師 (50516044)
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Co-Investigator(Kenkyū-buntansha) |
徳永 大作 京都府立医科大学, 医学(系)研究科(研究院), 准教授 (90343409)
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Research Collaborator |
KIDO Masamitsu
ONISHI Okkihiro
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Project Period (FY) |
2014-04-01 – 2017-03-31
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Project Status |
Completed (Fiscal Year 2016)
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Budget Amount *help |
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2016: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2015: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2014: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
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Keywords | 整形外科学 / MRI / 関節軟骨 / 造影剤 |
Outline of Final Research Achievements |
MRI is used recently to assess the degeneration of articular cartilage. However articular cartilage is a thin layer and has same signal intensity as the joint fluid, so it is difficult to distinguish between the articular cartilage and the adjacent joint fluid on MR images. To depict the articular cartilage, we obtained MR images after injecting a contrast agent with manganese ion. The agent depressed the signal intensity of the joint fluid, which made a contrast between the articular cartilage and the joint fluid. This new method enabled us to visualize the articular cartilage more vividly and in the earlier stage than the conventional method.
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Report
(4 results)
Research Products
(16 results)
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[Presentation] 足関節脱臼骨折に対するMR画像解析2015
Author(s)
城戸 優充, 生駒 和也, 原 佑輔, 今井 寛, 牧 昌弘, 大橋 鈴世, 久保 俊一
Organizer
第40回日本足の外科学会学術集会
Place of Presentation
千葉県浦安市ヒルトン東京ベイ
Year and Date
2015-10-29
Related Report
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