Measurement of regional cerebral blood flow by near infrared spectroscopy with indocyanin green

• Project/Area Number: 26462376
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Anesthesiology
• Research Institution: National Cardiovascular Center Research Institute
• Principal Investigator: Yoshitain Kenji 国立研究開発法人国立循環器病研究センター, 病院, 医長 (30524029)
• Co-Investigator(Kenkyū-buntansha): 大西 佳彦 国立研究開発法人国立循環器病研究センター, 病院, 部長 (40443501)
• Project Period (FY): 2014-04-01 – 2017-03-31
• Project Status: Completed (Fiscal Year 2016)
• Budget Amount: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000); Fiscal Year 2016: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000); Fiscal Year 2015: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000); Fiscal Year 2014: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
• Keywords: 脳血流 / 近赤外線分光法 / 脳血流測定 / インドシアニングリーン / 局所脳血流 / 局所脳酸素飽和度 / 頭蓋外血流

Outline of Final Research Achievements

Cerebral blood flow has been measured in facilities of radiology due to using radio isotope. We established the methodology to measure regional cerebral blood flow by using near infrared spectroscopy with indocyanine green, which enables to measure cerebral blood flow at bed side.

Research Products

• [Journal Article] Effect of posture and extracranial contamination on results of cerebral oximetry by near-infrared spectroscopy. (2017)
  • Author(s): Kato S, Yoshitani K, Kubota Y, Inatomi Y, Ohnishi Y.
  • Journal Title: J Anesth Volume: 31 Issue: 1 Pages: 103-110
  • DOI: 10.1007/s00540-016-2275-1
  • NAID: 40021101694
  • Peer Reviewed / Open Access
• [Journal Article] Cerebral Blood Flow Measurement by Near-Infrared Spectroscopy During Carotid Endarterectomy (2016)
  • Author(s): Shinya Kato, Kenji Yoshitani, Ohnishi Yoshihiko
  • Journal Title: Journal of Neurosurgical Anesthesiology Volume: 28 Pages: 1-5
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] 近赤外線モニター (2015)
  • Author(s): 吉谷健司 大西佳彦
  • Journal Title: 麻酔 Volume: 64 Pages: 473-477
  • Peer Reviewed / Acknowledgement Compliant
• [Presentation] Comparison of the FORE-SIGHT ELITE and the INVOS 5100C: Effects of hemoglobin concentration, area of the cerebrospinal fluid layer, and PaCO2 on rSO2 values (2016)
  • Author(s): Tomoyuki Iwai, Kenji Yoshitani, Yoshihiko Ohnishi
  • Organizer: アメリカ麻酔学会
  • Place of Presentation: アメリカ、イリノイ州シカゴ
  • Year and Date: 2016-10-22
  • Int'l Joint Research
• [Presentation] Comparison of the FORE-SIGHT ELITE and the INVOS 5100C: Effects of hemoglobin concentration, area of the cerebrospinal fluid layer, and PaCO2 on rSO2 values (2016)
  • Author(s): Tomoyuki Iwai, Kenji Yoshitani, Yoshihiko Ohnishi
  • Organizer: アメリカ神経麻酔学会
  • Place of Presentation: アメリカ、イリノイ州シカゴ
  • Int'l Joint Research
• [Presentation] Impact of posture and extra cranial contamination on cerebral oximetry by near infrared spectroscopy (2015)
  • Author(s): Shinya Kato, Kenji Yoshitani, Yoshihiko Ohnishi
  • Organizer: Annual meeting of American Society of Anesthesiologists
  • Place of Presentation: San Diego
  • Year and Date: 2015-10-26
  • Int'l Joint Research
• [Presentation] Effect of skull on regional cerebral oxygen saturation measured by near infrared spectroscopy in patients who underwent cranioplasty after extra decompression surgery (2015)
  • Author(s): Yosuke Kubota, Kenji Yoshitani, Shinya Kato, Yoshihiko Ohnishi
  • Organizer: Annual meeting of Society for Neuroscience in Anesthesiology and Critical Care
  • Place of Presentation: San Diego
  • Year and Date: 2015-10-23
  • Int'l Joint Research
• [Presentation] NIRS使用の注意点 ピットフォールと問題点 シンポジウム (2014)
  • Author(s): 吉谷健司 大西佳彦
  • Organizer: 第34回日本臨床麻酔学会学術集会
  • Place of Presentation: 東京
  • Year and Date: 2014-11-01 – 2014-11-03
  • Invited
• [Presentation] Cerebral blood flow measurement by near infrared spectroscopy in carotid endarterectomy (2014)
  • Author(s): Shinya Kato, Kenji Yoshitani, Yoshihiko Ohnishi
  • Organizer: Annual meeting of American Society of Anesthesiologists
  • Place of Presentation: New Orleans
  • Year and Date: 2014-10-11 – 2014-10-15
• [Presentation] Effect of Extracranial Blood Flow on Cerebral Oximetry: A Comparison of Three Cerebral Oximetry devices, NIRO-200NX, INVOS 5100S and TRS (2014)
  • Author(s): Kuniko Morishima, Kenji Yoshitani, Yoshihiko Ohnishi
  • Organizer: Annual meeting of American Society of Anesthesiologists
  • Place of Presentation: New Orleans
  • Year and Date: 2014-10-11 – 2014-10-15
• [Presentation] Effect of propofol, sevoflurane and desflurane on regional cerebral blood flow measured by near infrared spectroscopy (2014)
  • Author(s): Yousuke Kubota, Kenji Yoshitani, Yuzuru Inatomi, Shinya Kato, Yoshihiko Ohnishi
  • Organizer: Annual meeting of American Society of Anesthesiologists
  • Place of Presentation: New Orleans
  • Year and Date: 2014-10-11 – 2014-10-15
• [Presentation] Cerebral blood flow measurement by near infrared spectroscopy in carotid endarterectomy (2014)
  • Author(s): Shinya Kato, Kenji Yoshitani, Yoshihiko Ohnishi
  • Organizer: Annual meeting of Society for Neuroscience in Anesthesiology and Critical Care
  • Place of Presentation: New Orleans
  • Year and Date: 2014-10-10
• [Presentation] Effect of propofol, sevoflurane and desflurane on regional cerebral blood flow measured by near infrared spectroscopy (2014)
  • Author(s): Yousuke Kubota, Kenji Yoshitani, Yuzuru Inatomi, Shinya Kato, Yoshihiko Ohnishi
  • Organizer: Annual meeting of Society for Neuroscience in Anesthesiology and Critical Care
  • Place of Presentation: New Orleans
  • Year and Date: 2014-10-10
• [Presentation] Effect of Extracranial Blood Flow on Cerebral Oximetry: A Comparison of Three Cerebral Oximetry devices, NIRO-200NX, INVOS 5100S and TRS (2014)
  • Author(s): Kuniko Morishima, Kenji Yoshitani, Yoshihiko Ohnishi
  • Organizer: Annual meeting of Society for Neuroscience in Anesthesiology and Critical Care
  • Place of Presentation: New Orleans
  • Year and Date: 2014-10-10
• [Presentation] 近赤外線分光法を用いた局所脳酸素飽和度における頭蓋外血流の影響に関する研究 (2014)
  • Author(s): 森島久仁子 吉谷健司 大西佳彦
  • Organizer: 第61回日本麻酔科学会学術集会総会
  • Place of Presentation: 横浜
  • Year and Date: 2014-05-15 – 2014-05-17
• [Book] Neuroanesthesia and Cerebrospinal Protection (2016)
  • Author(s): Ken Kuwajima, Kenji Yoshitani
  • Total Pages: 7
  • Publisher: Springer
• [Book] Neuroanesthesia and Cerebrospinal Protection (2015)
  • Author(s): Ken Kuwajima, Kenji Yoshitnai
  • Total Pages: 9
  • Publisher: Springer