Establishment of standard treatment for Renal tumor patients using nomogram for Japanese

• Project/Area Number: 26462393
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Urology
• Research Institution: Tohoku University
• Principal Investigator: Hideo Saito 東北大学, 医学系研究科, 非常勤講師 (00466559)
• Co-Investigator(Kenkyū-buntansha): 荒井 陽一 東北大学, 医学系研究科, 教授 (50193058) ; 山口 拓洋 東北大学, 医学系研究科, 教授 (50313101) ; 伊藤 明宏 東北大学, 医学系研究科, 准教授 (70344661) ; 山田 成幸 東北大学, 医学系研究科, 非常勤講師 (60509256)
• Project Period (FY): 2014-04-01 – 2017-03-31
• Project Status: Completed (Fiscal Year 2016)
• Budget Amount: ¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000); Fiscal Year 2016: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000); Fiscal Year 2015: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000); Fiscal Year 2014: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
• Keywords: 腎癌 / 腎機能 / 小径腎腫瘍 / 腎血管筋脂肪腫

Outline of Final Research Achievements

Information about laparoscopic partial nephrectomy (LPN) in Japan is sparse. Then, a nationwide survey was performed. 1,375 patients underwent LPN and urological complications (grade 3-5) were very rare. Most of the tumor recurrences occurred as metastasis, and surgical margin status appears to have little impact on oncological outcome.
To evaluate renal function one year after radical nephrectomy, the preoperative predictors of postnephrectomy renal function were investigated and equations to predict the estimated glomerular filtration rate (eGFR) one year after RN were developed. The developed equations enable better prediction of eGFR one year after RN. The equations will be useful for preoperative patient counseling and selection of the type of surgical procedure in elective partial or RN cases.

Research Products

• [Journal Article] Clinical predictors of the estimated glomerular filtration rate one year after radical nephrectomy in Japanese patients (2017)
  • Author(s): Shuichi Shimada, Hideo Saito, Yoshihide Kawasaki, Shinichi Yamashita, Hisanobu Adachi, Narihiko Kakoi, Takashige Namima, Masahiko Sato, Atsushi Kyan, Koji Mitsuzuka, Akihiro Ito, Takuhiro Yamaguch iand Yoichi Arai
  • Journal Title: Investigative and Clinical Urology Volume: 印刷中
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Presentation] 東北大学関連施設における腎腫瘍患者１，０７９例のトレンド (2014)
  • Author(s): 齋藤英郎、伊藤明宏、嶋田修一、荒井陽一
  • Organizer: 第１０２回 日本泌尿器科学会総会
  • Place of Presentation: 神戸（神戸国際会議場）
  • Year and Date: 2014-04-26