| Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2016: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2015: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2014: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Outline of Final Research Achievements |
We continued to develop diagnostic system to identify urethral lesions of the prostatic urethra responsible for voiding dysfunction. The purpose of the research is to offer endoscopic “focal therapy” for male patients with voiding dysfunction. After computing flow dynamics of intraluminal urine flow using solid model, we prepared phantom models of the prostatic urethra with or without bladder outlet obstruction surrounded by a material mimicking prostatic elasticity. Cross sectional plane of the phantom was monitored by ultrasonography. The data of the urethral motion was captured in a virtual urethral model, and coupled analysis was performed. When compared pressure distribution between normal and obstructed model at peak urine flow stage, prominent difference was observed at the bladder, bladder outlet and the sphincter level. The data corresponded with clinical findings, and would validate to detect the lesion responsible for voiding dysfunction.
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