| Project/Area Number |
26462444
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Urology
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| Research Institution | Kagawa University |
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Principal Investigator |
Sugimoto Mikio 香川大学, 医学部附属病院, 准教授 (10243768)
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| Co-Investigator(Kenkyū-buntansha) |
筧 善行 香川大学, 医学部, 教授 (20214273)
張 霞 香川大学, 医学部, 助教 (30524061)
林田 有史 香川大学, 医学部附属病院, 助教 (30615034)
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| Project Period (FY) |
2014-04-01 – 2017-03-31
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| Project Status |
Completed (Fiscal Year 2016)
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| Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2016: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2015: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2014: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
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| Keywords | 前立腺炎 / サイトカイン / ケモカイン / 前立腺肥大症 / 非細菌性慢性炎症 / 尿中マーカー / サイトカイン・ケモカイン |
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| Outline of Final Research Achievements |
We elucidated that some chemokines, including CCL2/MCP-1 and CXCL1/CINC-1, were elevated in the prostate and urine of non-bacterial prostatitis(NBP) model rats, and Eviprostat potently suppressed the increases in CCL2/MCP-1 and CXCL1/CINC-1. These chemokines are therefore candidate diagnostic biomarkers for nonbacterial chronic prostatic inflammation. However, in human urine, we could not detect the change of chemokines. Further study for detection in human urine is warranted.
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