| Budget Amount *help |
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2016: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2015: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2014: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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| Outline of Final Research Achievements |
We explored whether CollagenⅩⅨ, one of FACIT collagens, effects on the rhabdosphincter. We made CollageⅩⅨ knockout female mice and used 129/wild type female mice as control. We measured Leak Point Pressure as the functional assessment, and mean area of urethral lumen and urethal circumference of as morphological evaluations at 4week-old.
In resuls, there were no significant difference between two groups in functional and morphogical enaluations. So, CollagenⅩⅨ doesn’t involve with function of rhabdosphincter.
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