New model of patulous eustachian tube targeted for tissue surrounding of eustachian tube

• Project/Area Number: 26462545
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Otorhinolaryngology
• Research Institution: Tohoku University
• Principal Investigator: Toshiaki Kikuchi 東北大学, 医学系研究科, 非常勤講師 (20509418)
• Co-Investigator(Kenkyū-buntansha): 香取 幸夫 東北大学, 医学系研究科, 教授 (20261620) ; 池田 怜吉 東北大学, 医学系研究科, 非常勤講師 (30645742) ; 大島 猛史 東北医科薬科大学, 東北医科薬科大学病院, 感覚器センター長 (40241608)
• Project Period (FY): 2014-04-01 – 2017-03-31
• Project Status: Completed (Fiscal Year 2016)
• Budget Amount: ¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000); Fiscal Year 2016: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000); Fiscal Year 2015: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000); Fiscal Year 2014: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
• Keywords: 耳管開放症 / 中耳 / 耳管

Outline of Final Research Achievements

We tried animal explanation, however, did not acquire significant result. We next tried clinical evaluation of Patulous Eustachian tube patient and had good result as below. 1) Endoscope-assisted silicone plug insertion for patulous Eustachian tube patients. 2) Computed tomography findings of the bony portion of the Eustachian tube with or without patulous Eustachian tube patients. 3) Effectiveness of Kobayashi plug for 252 ears with chronic patulous Eustachian tube. 4) Tubal function tests with optional myringotomy detect Eustachian tube closing failure in acquired pars flaccida retraction cholesteatoma. 5) Relationship Between Clinical Test Results and Morphologic Severity Demonstrated by Sitting 3-D CT in Patients With Patulous Eustachian Tube.

Research Products

• [Journal Article] New Scoring System for Evaluating Patulous Eustachian Tube Patients. (2017)
  • Author(s): Ikeda R, Kikuchi T, Oshima H, Miyazaki H, Hidaka H, Kawase T, Katori Y, Kobayashi T.
  • Journal Title: Otol Neurotol. Volume: 印刷中 Issue: 5 Pages: 708-713
  • DOI: 10.1097/mao.0000000000001370
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] Endoscope-assisted silicone plug insertion for patulous Eustachian tube patients. (2017)
  • Author(s): Ikeda R, Kikuchi T, Kobayashi T.
  • Journal Title: Laryngoscope. Volume: 印刷中 Issue: 9 Pages: 2149-2151
  • DOI: 10.1002/lary.26498
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] Computed tomography findings of the bony portion of the Eustachian tube with or without patulous Eustachian tube patients. (2017)
  • Author(s): Ikeda R, Kikuchi T, Oshima H, Miyazaki H, Hidaka H, Kawase T, Katori Y, Kobayashi T.
  • Journal Title: Eur Arch Otorhinolaryngol. Volume: 2 Issue: 2 Pages: 781-786
  • DOI: 10.1007/s00405-016-4383-9
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] Effectiveness of Kobayashi plug for 252 ears with chronic patulous Eustachian tube. (2017)
  • Author(s): Kikuchi T, Ikeda R, Oshima H, Takata I, Kawase T, Oshima T, Katori Y, Kobayashi T.
  • Journal Title: Acta Otolaryngol. Volume: 3 Issue: 3 Pages: 253-258
  • DOI: 10.1080/00016489.2016.1231420
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] Relationship Between Clinical Test Results and Morphologic Severity Demonstrated by Sitting 3-D CT in Patients With Patulous Eustachian Tube. (2016)
  • Author(s): Ikeda R, Kikuchi T, Oshima H, Miyazaki H, Hidaka H, Kawase T, Katori Y, Kobayashi T.
  • Journal Title: Otol Neurotol. Volume: 7 Issue: 7 Pages: 908-913
  • DOI: 10.1097/mao.0000000000001102
  • Peer Reviewed / Acknowledgement Compliant