Research for suppressing the aging of the peripheral vestibular organs

• Project/Area Number: 26462550
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Otorhinolaryngology
• Research Institution: The University of Tokyo
• Principal Investigator: Ushio Munetaka 東京大学, 医学部附属病院, 臨床登録医 (70361483)
• Co-Investigator(Kenkyū-buntansha): 山下 真司 東京大学, 先端科学技術研究センター, 教授 (40239968) ; 鈴木 光也 東邦大学, 医学部, 教授 (50302724)
• Project Period (FY): 2014-04-01 – 2018-03-31
• Project Status: Completed (Fiscal Year 2017)
• Budget Amount: ¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000); Fiscal Year 2016: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000); Fiscal Year 2015: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000); Fiscal Year 2014: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
• Keywords: 前庭 / 半規管 / 電気刺激 / 老化 / 前庭動眼反射 / リハビリテーション

Outline of Final Research Achievements

For suppressing the aging of the peripheral vestibular organs, experimental system for performing vestibular stimulation for a guinea pig was constructed. Technique for stimulating the vestibular ganglion and inducing the eye movement was established, however we still cannot induce the eye movement exactly as we wanted. We are planning to reserve the vestibular ganglion cells by electric stimulation.