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Investigation of pathogenesis of age-related hearing loss- the relationship between the hearing loss and the cerebrovascular disorder

Research Project

Project/Area Number 26462552
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Otorhinolaryngology
Research InstitutionNiigata University

Principal Investigator

Morita Yuka  新潟大学, 医歯学総合病院, 講師 (60547602)

Project Period (FY) 2014-04-01 – 2018-03-31
Project Status Completed (Fiscal Year 2017)
Budget Amount *help
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2016: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2015: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2014: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Keywords加齢性難聴 / 脳血管障害 / 認知機能障害 / 疫学調査 / 認知障害
Outline of Final Research Achievements

Age-related deafness is a hearing loss that develops with age and gradually progresses, some reports say 40% of people over 65 years old were developed the deafness. The relationship between age-related hearing loss and cerebrovascular disorder is not clear yet.If these relationships are proved,it may be helpful in establishing how to prevent hearing loss.
In this study, model mouse and human epidemiological studies showed no clear relation to age-related hearing loss and cerebrovascular disorder.Furthermore, the presence of ApoE4 gene, which is regarded as a risk factor for Alzheimer's disease, also had no effect on hearing loss. However, we found a strong correlation with regard to the decline in cognitive function, which is considered to be a clue to future analysis.

Report

(5 results)
  • 2017 Annual Research Report   Final Research Report ( PDF )
  • 2016 Research-status Report
  • 2015 Research-status Report
  • 2014 Research-status Report
  • Research Products

    (5 results)

All 2018 2015 2014

All Presentation (5 results) (of which Int'l Joint Research: 1 results)

  • [Presentation] Risk factors of age-related hearing loss - The epidemiological study in Sado Island2018

    • Author(s)
      Yuka Morita, Kuniyuki Takahashi, Shinsuke Ohshima, Tatsuya Yamagishi, Yamato Kubota, Shuji Izumi, Arata Horii
    • Organizer
      17th Korea Japan Joint Meeting of Otorhinolaryngology Head and Neck Surgery
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 認知障害と加齢性難聴との関係について -疫学調査プロジェクト(PROST)データから2015

    • Author(s)
      森田由香 宮尾益道 山本 裕 髙橋 姿
    • Organizer
      第116回日本耳鼻咽喉科学会総会
    • Place of Presentation
      東京都東京国際フォーラム
    • Year and Date
      2015-05-20 – 2015-05-23
    • Related Report
      2014 Research-status Report
  • [Presentation] 認知障害と加齢性難聴との関係について―疫学調査プロジェクト(PROST)データから2015

    • Author(s)
      森田由香 宮尾益道 山本 裕 高橋 姿
    • Organizer
      第116回日本耳鼻咽喉科学会総会
    • Place of Presentation
      東京都国際フォーラム(東京都中央区)
    • Year and Date
      2015-05-20
    • Related Report
      2015 Research-status Report
  • [Presentation] Relationship between prevalence of presbycusis and risk factors2014

    • Author(s)
      Yuka Morita Masumichi Miyao Sugata Takahashi
    • Organizer
      The 7th Instructional Workshop of European Academy of Otology and Neuro-Otology
    • Place of Presentation
      Siena, Italy
    • Year and Date
      2014-09-13 – 2014-09-16
    • Related Report
      2014 Research-status Report
  • [Presentation] 加齢性難聴と脳血管障害との関係について -佐渡PROSTデータから2014

    • Author(s)
      森田由香 宮尾益道 髙橋 姿
    • Organizer
      第115回日本耳鼻咽喉科学会総会
    • Place of Presentation
      福岡市ヒルトン福岡シーホーク
    • Year and Date
      2014-05-14 – 2014-05-17
    • Related Report
      2014 Research-status Report

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Published: 2014-04-04   Modified: 2019-03-29  

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