Investigation of pathogenesis of age-related hearing loss- the relationship between the hearing loss and the cerebrovascular disorder
Project/Area Number |
26462552
|
Research Category |
Grant-in-Aid for Scientific Research (C)
|
Allocation Type | Multi-year Fund |
Section | 一般 |
Research Field |
Otorhinolaryngology
|
Research Institution | Niigata University |
Principal Investigator |
Morita Yuka 新潟大学, 医歯学総合病院, 講師 (60547602)
|
Project Period (FY) |
2014-04-01 – 2018-03-31
|
Project Status |
Completed (Fiscal Year 2017)
|
Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2016: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2015: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2014: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
|
Keywords | 加齢性難聴 / 脳血管障害 / 認知機能障害 / 疫学調査 / 認知障害 |
Outline of Final Research Achievements |
Age-related deafness is a hearing loss that develops with age and gradually progresses, some reports say 40% of people over 65 years old were developed the deafness. The relationship between age-related hearing loss and cerebrovascular disorder is not clear yet.If these relationships are proved,it may be helpful in establishing how to prevent hearing loss. In this study, model mouse and human epidemiological studies showed no clear relation to age-related hearing loss and cerebrovascular disorder.Furthermore, the presence of ApoE4 gene, which is regarded as a risk factor for Alzheimer's disease, also had no effect on hearing loss. However, we found a strong correlation with regard to the decline in cognitive function, which is considered to be a clue to future analysis.
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Report
(5 results)
Research Products
(5 results)