| Project/Area Number |
26462647
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Ophthalmology
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| Research Institution | Kitasato University |
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Principal Investigator |
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| Co-Investigator(Renkei-kenkyūsha) |
HANDA Tomoya 北里大学, 医療衛生学部, 教授 (20383648)
IKEDA Tetsuya 北里大学, 医学部, 助教 (40406947)
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| Research Collaborator |
GOSEKI Toshiaki
ASAKAWA Ken
TATSUI Sonoko
IWATA Yo
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| Project Period (FY) |
2014-04-01 – 2017-03-31
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| Project Status |
Completed (Fiscal Year 2016)
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| Budget Amount *help |
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2016: ¥130,000 (Direct Cost: ¥100,000、Indirect Cost: ¥30,000)
Fiscal Year 2015: ¥130,000 (Direct Cost: ¥100,000、Indirect Cost: ¥30,000)
Fiscal Year 2014: ¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
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| Keywords | NIRS / 新生児 / 視機能評価 |
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| Outline of Final Research Achievements |
Evaluating visual functions is difficult in infants. For objective evaluation, methods by measuring light reflex, electric retinogram (ERG), and visual evoked potentials have been used. Although objectivity of such measurement is high, examination is not minimally invasive. In this study, we used functional near-infrared spectroscopy (fNIRS) in a less invasive way to objectively evaluate visual functions of infants. We also measured light reflex at the same time. Then, we used ERG of skin-electrode type and compared with the results of fNIRS to confirm the accuracy. The results of fNIRS were about the same as the results obtained with other devices. Also, the test results of not only healthy infants but also infants with visual abnormality were consistent with the clinical findings. However, in some cases the results were different in every examination, so at this point, we should not determine visual functions only from the results of fNIRS but determine comprehensively.
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