| Budget Amount *help |
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2017: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2016: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Fiscal Year 2015: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2014: ¥130,000 (Direct Cost: ¥100,000、Indirect Cost: ¥30,000)
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| Outline of Final Research Achievements |
Atropine eye drop (At.) is known to reduce myopia progression. In this study, we studied the treatment effects and side effects produced by diluted (0.01%) At.in Japanese children with myopia. After applying of 0.01% At, subjective measurements of accommodative lag and pupillary diameter showed that accuracy of accommodation was well preserved but the pupils were slightly dilated, indicating the possibility of photophobia during outdoor activity. Mean myopia progression for 2 years was -1.43 and -1.52D for treated and control groups, respectively. Mean elongation of ocular axial length was 0.67 and 0.70mm for treated and control groups, respectively. The mean treatment effects (0.09D and 0.03mm) were not significant. These results suggested that 0.01% At. is ineffective or the effect is small as a clinical treatment and thus cannot to be recommended to children as a preventive treatment for myopia progression.
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