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Development of a novel method to measure visual field

Research Project

Project/Area Number 26462679
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Ophthalmology
Research InstitutionThe University of Tokyo

Principal Investigator

Asaoka Ryo  東京大学, 医学部附属病院, 特任講師 (00362202)

Research Collaborator MURATA HIROSHI  東京大学, 医学部附属病院, 助教 (80635748)
FUJINO YURI  東京大学, 医学部附属病院, 特任研究員 (20768254)
MATSUURA MASATO  東京大学, 医学部附属病院, 特任研究員 (00768351)
Project Period (FY) 2014-04-01 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2016: ¥520,000 (Direct Cost: ¥400,000、Indirect Cost: ¥120,000)
Fiscal Year 2015: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2014: ¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Keywords緑内障 / 視野進行予測 / 視野測定
Outline of Final Research Achievements

A database of glaucomatous visual field was developed with 1348 eyes from 10 institutes in Japan. Using this database, it was suggested it was useful to regress visual field result against intraocular pressure integrated time rather than regressing against time. Also, it was suggested it was usefl to use deep learning method to detect early glaucomatous visual field change. It was suggested it was useful to combine these approaches with the variational Bayes linear regression, and the development of visual field measurement algorithm using these outcomes is on-going.

Report

(4 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Research-status Report
  • 2014 Research-status Report
  • Research Products

    (38 results)

All 2017 2016 2015 2014

All Journal Article (16 results) (of which Int'l Joint Research: 3 results,  Peer Reviewed: 16 results,  Open Access: 13 results,  Acknowledgement Compliant: 6 results) Presentation (20 results) (of which Int'l Joint Research: 6 results,  Invited: 3 results) Patent(Industrial Property Rights) (2 results)

  • [Journal Article] The usefulness of CorvisST Tonometry and the Ocular Response Analyzer to assess the progression of glaucoma2017

    • Author(s)
      Matsuura M, Hirasawa K, Murata H, Nakakura S, Kiuchi Y, Asaoka R
    • Journal Title

      Sci Rep

      Volume: 17 Issue: 1 Pages: 40798-40798

    • DOI

      10.1038/srep40798

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Developing an Item Bank to Measure Quality of Life in Individuals With Glaucoma, and the Results of the Interview With Patients: The Effect of Visual Function, Visual Field Progression Rate, Medical, and Surgical Treatments on Quality of Life2017

    • Author(s)
      Matsuura M, Hirasawa K, Hirasawa H, Yanagisawa M, Murata H, Mayama C, Asaoka R
    • Journal Title

      J glaucoma

      Volume: 26 Issue: 2 Pages: e64-e73

    • DOI

      10.1097/ijg.0000000000000554

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Evaluation of Glaucoma Progression in Large-Scale Clinical Data: The Japanese Archive of Multicentral Databases in Glaucoma (JAMDIG).2016

    • Author(s)
      Fujino Y, Asaoka R, Murata H, Miki A, Tanito M, Mizoue S, Mori K, Suzuki K, Yamashita T, Kashiwagi K, Shoji N
    • Journal Title

      Invest Ophthalmol Vis Sci.

      Volume: 57 Issue: 4 Pages: 2012-2020

    • DOI

      10.1167/iovs.15-19046

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] A novel method to predict visual field progression more accurately, using intraocular pressure measurements in glaucoma patients2016

    • Author(s)
      Asaoka R, Fujino Y, Murata H, Miki A, Tanito M, Mizoue S, Mori K, Suzuki K, Yamashita T, Kashiwagi K, Shoji N, Japanese Archive of Multicentral Database in Glaucoma (JAMDIG) construction group
    • Journal Title

      Sci Rep

      Volume: 26 Issue: 1 Pages: 31728-31728

    • DOI

      10.1038/srep31728

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Effects of ocular and systemic factors on the progression of glaucomatous visual field damage in various sectors.2016

    • Author(s)
      Asaoka R, Murata H, Fujino Y, Hirasawa K, Tanito M, Mizoue S, Mori K, Suzuki K, Yamashita T, Kashiwagi K, Miki A, Shoji N
    • Journal Title

      Br J Ophthalmol.

      Volume: - Issue: 8 Pages: 1071-1075

    • DOI

      10.1136/bjophthalmol-2016-309643

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Detecting Preperimetric Glaucoma with Standard Automated Perimetry Using a Deep Learning Classifier2016

    • Author(s)
      Asaoka R, Murata H, Iwase A, Araie M
    • Journal Title

      Ophthalmology

      Volume: 123 Issue: 9 Pages: 1974-1980

    • DOI

      10.1016/j.ophtha.2016.05.029

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Validating the Usefulness of the "Random Forests" Classifier to Diagnose Early Glaucoma With Optical Coherence Tomography2016

    • Author(s)
      Asaoka R, Hirasawa K, Iwase A, Fujino Y, Murata H, Shoji N, Araie M
    • Journal Title

      Am J Ophthalmol

      Volume: 174 Pages: 95-103

    • DOI

      10.1016/j.ajo.2016.11.001

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The usefulness of gaze tracking as an index of visual field reliability in glaucoma patients.2015

    • Author(s)
      Ishiyama Y, Murata H, Hirasawa H, Asaoka R.
    • Journal Title

      Invest Ophthalmol Vis Sci

      Volume: 56 Issue: 13 Pages: 7801-7805

    • DOI

      10.1167/iovs.15-17988

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] The usefulness of gaze tracking as an index of visual field reliability in glaucoma patients.2015

    • Author(s)
      Ishiyama Y, Murata H, Asaoka R
    • Journal Title

      Invest Ophthalmol Vis Sci

      Volume: 56 Issue: 11 Pages: 6233-6

    • DOI

      10.1167/iovs.15-17661

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Applying 'Lasso' regression to predict future visual field progression in glaucoma2015

    • Author(s)
      Y. Fujino, H. Murata, C. Mayama and R. Asaoka
    • Journal Title

      Investigative ophthalmology & visual science

      Volume: 56 Issue: 4 Pages: 2334-9

    • DOI

      10.1167/iovs.15-16445

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] A new approach to measure visual field progression in glaucoma patients using variational bayes linear regression2014

    • Author(s)
      H. Murata, M. Araie and R. Asaoka
    • Journal Title

      Investigative ophthalmology & visual science

      Volume: 12 Issue: 12 Pages: 8386-8392

    • DOI

      10.1167/iovs.14-14625

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] An objective evaluation of gaze tracking in Humphrey perimetry and the relation with the reproducibility of visual fields: a pilot study in glaucoma2014

    • Author(s)
      Y. Ishiyama, H. Murata, C. Mayama and R. Asaoka
    • Journal Title

      Investigative ophthalmology & visual science

      Volume: 55 Issue: 12 Pages: 8149-52

    • DOI

      10.1167/iovs.14-15541

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Clustering visual field test points based on rates of progression to improve the prediction of future damage.2014

    • Author(s)
      Hirasawa K, Murata H, Hirasawa H, Mayama C, Asaoka R.
    • Journal Title

      Invest Ophthalmol Vis Sci.

      Volume: 55 Issue: 11 Pages: 7681-5

    • DOI

      10.1167/iovs.14-15040

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Evaluation of various machine learning methods to predict vision-related quality of life from visual field data and visual acuity in patients with glaucoma.2014

    • Author(s)
      Hirasawa H, Murata H, Mayama C, Araie M, Asaoka R.
    • Journal Title

      Br J Ophthalmol.

      Volume: 98(9) Issue: 9 Pages: 1230-5

    • DOI

      10.1136/bjophthalmol-2013-304319

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Identifying "preperimetric" glaucoma in standard automated perimetry visual fields2014

    • Author(s)
      Asaoka R, Iwase A, Hirasawa K, Murata H, Araie M
    • Journal Title

      Invest Ophthalmol Vis Sci

      Volume: 12 Issue: 12 Pages: 7814-7820

    • DOI

      10.1167/iovs.14-15120

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] The Relationship between Central Visual Field Damage and Motor Vehicle Collisions in Primary Open-Angle Glaucoma Patients2014

    • Author(s)
      Yuki K, Asaoka R, Tsubota K
    • Journal Title

      PlosOne

      Volume: 12 Issue: 12 Pages: e115572-e115572

    • DOI

      10.1371/journal.pone.0115572

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Presentation] To diagnose glaucoma based on spectral domain optical coherence tomography (SD-OCT) measurements using the 'Random Forests’ method.2017

    • Author(s)
      朝岡亮
    • Organizer
      32nd Asia-Pacific Academy of Ophthalmology
    • Place of Presentation
      Singapore
    • Year and Date
      2017-03-01
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Investigation of the usefulness of Octopus EyeSuite’s Cluster Trend Analysis2016

    • Author(s)
      朝岡亮、村田博史
    • Organizer
      United Kingdom and Eire Glaucoma Society
    • Place of Presentation
      英国、チェルトナム
    • Year and Date
      2016-11-06
    • Related Report
      2016 Annual Research Report
  • [Presentation] Adjusting circumpapillary retinal nerve fiber layer thickness profile measured with optical coherence tomography using the retinal artery position improves the structure-function relationship2016

    • Author(s)
      Fujino Y, Yamashita T, Yanagisawa M, Murata H, Asaoka R
    • Organizer
      国際視野学会
    • Place of Presentation
      Italy, Udine
    • Year and Date
      2016-09-27
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] The usefulness of CorvisST and the Ocular Response Analyzer to assess the progression of glaucoma2016

    • Author(s)
      Matsuura M, Hirasawa K, Murata H, Nakao Y, Nakakura S, Kiuchi Y, Asaoka R
    • Organizer
      国際視野学会
    • Place of Presentation
      Italy, Udine
    • Year and Date
      2016-09-27
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Validating variational Bayes linear regression model with multicentral data2016

    • Author(s)
      Murata H, Fujino Y, Asaoka R
    • Organizer
      国際視野学会
    • Place of Presentation
      Italy, Udine
    • Year and Date
      2016-09-27
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Investigating the usefulness of cluster trend analysis2016

    • Author(s)
      Aoki S, Murata H, Asaoka R
    • Organizer
      国際視野学会
    • Place of Presentation
      Italy, Udine
    • Year and Date
      2016-09-27
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 網膜動脈位置での補正による緑内障における構造機能連関の改善2016

    • Author(s)
      藤野友里、山下高明、柳沢美衣子、村田博史、朝岡亮
    • Organizer
      第27回日本緑内障学会
    • Place of Presentation
      横浜
    • Year and Date
      2016-09-17
    • Related Report
      2016 Annual Research Report
  • [Presentation] Corvis STによる角膜生体力学的特性と緑内障視野進行速度の関連の検討2016

    • Author(s)
      松浦将人、平澤一法、村田博史、中尾善隆、中倉俊佑、木内良明、朝岡亮
    • Organizer
      第27回日本緑内障学会
    • Place of Presentation
      横浜
    • Year and Date
      2016-09-17
    • Related Report
      2016 Annual Research Report
  • [Presentation] 日本人後ろ向き多施設緑内障データベース(JAMDIG) 緑内障視野進行の評価2016

    • Author(s)
      藤野友里、朝岡亮、村田博史、三木篤也、谷戸正樹、溝上史郎、森和彦、鈴木克佳、山下高明、柏木賢治、庄司信行
    • Organizer
      第5回日本視野学会学術集会
    • Place of Presentation
      神戸
    • Year and Date
      2016-05-14
    • Related Report
      2016 Annual Research Report
  • [Presentation] 緑内障の機能―構造解析におけるゲイズトラック記録および信頼性指標の有用性2016

    • Author(s)
      平澤裕代、石山由佳子、村田博史、朝岡亮
    • Organizer
      第120回日本眼科学会総会
    • Place of Presentation
      仙台
    • Year and Date
      2016-04-07
    • Related Report
      2016 Annual Research Report
  • [Presentation] 緑内障の構造-機能解析におけるゲイズトラック記録および信頼性指標の有用性2016

    • Author(s)
      平澤裕代、村田博史、朝岡亮
    • Organizer
      第120回日本眼科学会総会
    • Place of Presentation
      仙台
    • Year and Date
      2016-04-07
    • Related Report
      2015 Research-status Report
  • [Presentation] Data augmentation for predicting future visual field.2016

    • Author(s)
      Murata H, Asaoka R
    • Organizer
      World Ophthalmology Conference
    • Place of Presentation
      メキシコ、Guadalajara
    • Year and Date
      2016-02-05
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research
  • [Presentation] タイムシフトによる視野予測改善2015

    • Author(s)
      村田博史、朝岡亮
    • Organizer
      第26回日本緑内障学会
    • Place of Presentation
      ウィンク愛知(愛知県名古屋市)
    • Year and Date
      2015-09-12
    • Related Report
      2015 Research-status Report
  • [Presentation] 視野予測モデルの予測誤差に及ぼす因子の検討2015

    • Author(s)
      村田博史、朝岡亮
    • Organizer
      第119回日本眼科学会総会
    • Place of Presentation
      札幌
    • Year and Date
      2015-04-16 – 2015-04-19
    • Related Report
      2014 Research-status Report
  • [Presentation] 緑内障・視神経症「緑内障診断・現在と近未来」2015

    • Author(s)
      朝岡亮
    • Organizer
      第119回日本眼科学会総会
    • Place of Presentation
      札幌
    • Year and Date
      2015-04-16
    • Related Report
      2015 Research-status Report
    • Invited
  • [Presentation] MDとゲイズトラッキング、視野信頼性指標の関連に関する検討2014

    • Author(s)
      石山 由佳子、村田博史、間山千尋、朝岡亮
    • Organizer
      第119回日本眼科学会総会
    • Place of Presentation
      神戸
    • Year and Date
      2014-10-13 – 2014-10-16
    • Related Report
      2014 Research-status Report
  • [Presentation] ベイズ線形回帰を用いた視野予測2014

    • Author(s)
      村田博史、朝岡亮
    • Organizer
      第68回日本臨床眼科学会
    • Place of Presentation
      神戸
    • Year and Date
      2014-10-13 – 2014-10-16
    • Related Report
      2014 Research-status Report
  • [Presentation] シンポジウム 視野検査を活かして守る -the goal of visual field test- 統計解析で守る2014

    • Author(s)
      朝岡亮
    • Organizer
      第25回日本緑内障学会 2014 大阪
    • Place of Presentation
      大阪
    • Year and Date
      2014-09-19 – 2014-09-21
    • Related Report
      2014 Research-status Report
    • Invited
  • [Presentation] The gaze tracking and the test-retest reproducibility of visual field2014

    • Author(s)
      Ishiyama Y, Murata H, Mayama C, Asaoka R.
    • Organizer
      21th International Imaging and Perimetry Symposium
    • Place of Presentation
      New York
    • Year and Date
      2014-09-09 – 2014-09-12
    • Related Report
      2014 Research-status Report
  • [Presentation] Comparisons of robust linear regression and simple linear regression models in predicting visual field progression2014

    • Author(s)
      Taketani Y, Murata H, Asaoka R
    • Organizer
      21th International Imaging and Perimetry Symposium
    • Place of Presentation
      New York
    • Year and Date
      2014-09-09 – 2014-09-12
    • Related Report
      2014 Research-status Report
  • [Patent(Industrial Property Rights)] 視野検査装置2016

    • Inventor(s)
      山西健司、上坂俊允、森野 佳生、朝岡亮、村田博史
    • Industrial Property Rights Holder
      山西健司、上坂俊允、森野 佳生、朝岡亮、村田博史
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2016-215556
    • Filing Date
      2016-11-02
    • Related Report
      2016 Annual Research Report
  • [Patent(Industrial Property Rights)] 視野検査装置2015

    • Inventor(s)
      朝岡亮
    • Industrial Property Rights Holder
      朝岡亮
    • Industrial Property Rights Type
      特許
    • Filing Date
      2015-05-28
    • Related Report
      2015 Research-status Report

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Published: 2014-04-04   Modified: 2018-03-22  

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