| Budget Amount *help |
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2016: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2015: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2014: ¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
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| Outline of Final Research Achievements |
①The 204 cases were analyzed by GWAS. Assessment of rs8032158 revealed that in the dominant mode of inheritance, the severe keloid group had significant ORs compared with both the controls and the mild keloid group. Thus, rs8032158 associated strongly with severe keloids.
②The retrospective cross-sectional study involved 304 consecutive patients with keloids who were surgically treated in our hospital. Their blood pressure (BP), age and gender, and the size and number of their keloids before surgery were recorded. Ordinal logistic regression analyses showed that BP associated significantly with both keloid size and number.
③Vascular endothelial cells were sorted by magnetic activated cell sorter. Gene expression of these cells is studied. The analysis is undergoing.
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