| Project/Area Number |
26462858
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Pathobiological dentistry/Dental radiology
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| Research Institution | Nihon University |
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Principal Investigator |
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| Project Period (FY) |
2014-04-01 – 2017-03-31
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| Project Status |
Completed (Fiscal Year 2016)
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| Budget Amount *help |
¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Fiscal Year 2016: ¥260,000 (Direct Cost: ¥200,000、Indirect Cost: ¥60,000)
Fiscal Year 2015: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2014: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
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| Keywords | 口臭 / 検査 / 検査キット / 口腔細菌 / VSC / 硫化水素 / メチルメルカプタン / Veillonella / 口臭測定 / 口臭簡易検出キット / 細菌学的手法 |
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| Outline of Final Research Achievements |
Halitosis affects about one in four adults and frequently is caused by bacteria infecting the dorsal surface of the tongue and producing volatile sulfur compounds (VSCs). The aim of this study was to develop of the simple oral halitosis detection kit using culture method. This study was approved by the Ethics Committee of Nihon University School of Dentistry, Matsudo (EC 12-014). Halitosis was confirmed by means of organoleptic assessment and VSC levels measured using sensor gas chromatograph, ODSA-P2 (FIS, Hyogo, Japan).
It was indicated that the simple oral halitosis detection kit using culture method developed in this study is useful clinically, and can greatly contribute to the halitosis diagnosis.
Moreover, after investigating of oral bacteria concerned with halitosis, it was suggested that genus Veillonella correlated with halitosis principally.
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