In situ analysis of temporal and spatial dynamics of oral biofilm
Project/Area Number |
26462878
|
Research Category |
Grant-in-Aid for Scientific Research (C)
|
Allocation Type | Multi-year Fund |
Section | 一般 |
Research Field |
Conservative dentistry
|
Research Institution | Osaka University |
Principal Investigator |
Asahi Yoko 大阪大学, 歯学研究科, 助教 (50456943)
|
Co-Investigator(Kenkyū-buntansha) |
野杁 由一郎 新潟大学, 医歯学系, 教授 (50218286)
三浦 治郎 大阪大学, 歯学部附属病院, 助教 (70437383)
恵比須 繁之 大阪大学, 歯学研究科, 特任教授 (50116000)
|
Project Period (FY) |
2014-04-01 – 2017-03-31
|
Project Status |
Completed (Fiscal Year 2016)
|
Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2016: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2015: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2014: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
|
Keywords | バイオフィルム / in situバイオフィルムモデル / 歯科 / 歯内治療学 / 歯学 |
Outline of Final Research Achievements |
Using the in situ biofilm model that reproduces supragingival biofilm, we investigated the temporal dynamics of biofilm-forming bacterial species during the dental biofilm formation. As a results, the initial population of facultative anaerobic bacteria was replaced with the population of gram-negative anaerobic bacteria during dental biofilm formation. Also, in a method using an ionic liquid that is a new scanning electron microscopy observation method, ionic liquids suitable for biofilm observation was evaluated.
|
Report
(4 results)
Research Products
(12 results)
-
[Journal Article] Temporal dynamics of bacterial microbiota in the human oral cavity determined using an in situ model of dental biofilms2016
Author(s)
Wake N, Asahi Y, Noiri Y, Hayashi M, Motooka D, Nakamura S, Gotoh K, Miura J, Machi H, Iida T, Ebisu S.
-
Journal Title
npj Biofilms and Microbiome
Volume: 2
Issue: 1
Pages: 16018-16018
DOI
Related Report
Peer Reviewed / Open Access / Acknowledgement Compliant
-
-
-
-
-
-
-
-
-
-
-