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Practical use of materials for endodontic treatment to promote the reproduction of the hard tissue having an antibacterial effect

Research Project

Project/Area Number 26462907
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Conservative dentistry
Research InstitutionKyushu University of Health and Welfare

Principal Investigator

Nakamura Mariko  九州保健福祉大学, 保健科学部, 教授 (90284067)

Co-Investigator(Renkei-kenkyūsha) Ito Yoshihiro  国立研究開発法人理化学研究所, 創発物性科学研究センター, チームリーダー (40192497)
Yoshida Yasuhiro  北海道大学, 大学院歯学研究院 生体材料工学教室, 教授 (90281162)
Project Period (FY) 2014-04-01 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2016: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2015: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2014: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Keywordsリン酸化プルラン / 可視光硬化型ゼラチン
Outline of Final Research Achievements

It was provided that the compressive strength of phosphorylated-pullulan (PPL)was higher than α-tricalcium phosphate cement (TCP) and the shear bond strength to apatite and titanium of PPL was higher than TCP. And we removed entotoxins from PPL. It was appeared that PPL was appropriate as root canal filling materials.
A novel photo-cross-linkable gelatin (gelatin-FA) was rapidly cross-linked by visible light with Rose Bengal, a light sensitizer. It was confirmed that geratin-FA was cross-linked with another materials, a light sensitizer. It was suggested to be the materials which we could use as toxic few materials widely.

Report

(4 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Research-status Report
  • 2014 Research-status Report
  • Research Products

    (8 results)

All 2016 2015 2014

All Journal Article (4 results) (of which Int'l Joint Research: 1 results,  Peer Reviewed: 4 results,  Open Access: 1 results) Presentation (4 results)

  • [Journal Article] Cytocompatibility of HeLa cells to nano-sized ceramics particles2016

    • Author(s)
      E. Seitoku, S. Abe, T. Kusaka, M. Nakamura, S. Inoue, Y. Yoshida and H. Sano
    • Journal Title

      J. Nanoscience and Nanotechnology

      Volume: 16 Issue: 4 Pages: 3373-3377

    • DOI

      10.1166/jnn.2016.12309

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Assessment of size and morphological effects of ceramics nanoparticles on their biocompatibility2016

    • Author(s)
      S. Tsuchiya, S. Abe, Y. Era, Y. Nakagawa, M. Nakamura, T, Kusaka, Y, Yoshida, T. Yonezawa, J. Iida
    • Journal Title

      Nanoscience and Nanotechnology Letters

      Volume: 8 Issue: 4 Pages: 329-334

    • DOI

      10.1166/nnl.2016.2139

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Density functional theory study on oligosilane-functionalized C-60 fullerene2016

    • Author(s)
      S. Yoshizawa, S. Abe, M. Mutoh, T. Kusaka, M. Nakamura, Y. Yoshida, J. Iida, H. Kawabata and H. Tachikawa
    • Journal Title

      Jpn. J. Appl. Phys.

      Volume: 56 Issue: 1S Pages: 01AE03-01AE03

    • DOI

      10.7567/jjap.56.01ae03

    • NAID

      210000147387

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Bone engineering by phosphorylated-pullulan and β-TCP composite.2015

    • Author(s)
      Takahata T, Okihara T, Yoshida Y, Yoshihara K, Shiozaki Y, Yoshida A, Yamane K, Watanabe N, Yoshimura M, Nakamura M, Irie M, Van Meerbeek B, Tanaka M, Ozaki T, Matsukawa A.
    • Journal Title

      Biomed Mater.

      Volume: 10 Issue: 6 Pages: 065009-065009

    • DOI

      10.1088/1748-6041/10/6/065009

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Presentation] Cytocompatibility of several nano-sized ceramics particles: In vitro study2016

    • Author(s)
      Y. Era, S. Abe, A. Nakagawa, M. Nakamura, Y. Yoshida
    • Organizer
      The 17th Chitose International Forum on Photonics Science and Technology
    • Place of Presentation
      Chitose
    • Year and Date
      2016-11-14
    • Related Report
      2016 Annual Research Report
  • [Presentation] Assessment of the cytocompatibility of ceramic nanoparticles with several types of cells2016

    • Author(s)
      Y. Era, S. Abe, Y. Nakagawa, A. Hyono, M. Nakamura, T. Kusaka, Y. Yoshida
    • Organizer
      AsiaNANO 2016
    • Place of Presentation
      Sapporo
    • Year and Date
      2016-10-10
    • Related Report
      2016 Annual Research Report
  • [Presentation] 新しい可視光硬化ゼラチンを用いた家兎骨軟骨欠損モデルにおける組織修復効果2014

    • Author(s)
      馬崎哲朗,山根健太郎,吉田晶,松川昭博,中村真理子,吉田靖弘,北嶋隆,伊藤嘉浩,尾崎敏文
    • Organizer
      第29回日本整形外科学会基礎学術集会
    • Place of Presentation
      鹿児島,城山観光ホテル
    • Year and Date
      2014-10-09 – 2014-10-10
    • Related Report
      2014 Research-status Report
  • [Presentation] 新規生体材料によるインプラントコーティング技術2014

    • Author(s)
      香川洋平,馬崎哲朗,山根健太郎,篠原健介,吉田晶,松川昭博,中村真理子,吉田靖弘,北嶋隆,伊藤嘉浩,尾崎敏文
    • Organizer
      第29回日本整形外科学会基礎学術集会
    • Place of Presentation
      鹿児島,城山観光ホテル
    • Year and Date
      2014-10-09 – 2014-10-10
    • Related Report
      2014 Research-status Report

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Published: 2014-04-04   Modified: 2018-03-22  

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