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Elucidation of pathology of periimplantisis using metagenomic analysis

Research Project

Project/Area Number 26462929
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Prosthodontics/ Dental materials science and
Research InstitutionNagasaki University

Principal Investigator

WATAMOTO Takao  長崎大学, 医歯薬学総合研究科(歯学系), 客員研究員 (60420444)

Co-Investigator(Kenkyū-buntansha) 加藤 初実  長崎大学, 病院(歯学系), 医員 (30613608)
澤瀬 隆  長崎大学, 医歯薬学総合研究科(歯学系), 教授 (80253681)
Project Period (FY) 2014-04-01 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2016: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2015: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2014: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
Keywordsマイクロバイオーム / インプラント / 歯周組織 / メタジェノミクス / デンタルインプラント / インプラント周囲炎
Outline of Final Research Achievements

Microbiome analysis can detect all microorganisms, especially bacteria that cannot be cultured, and obtain genome information. It is very effective method that can analyze bacterial composition and function. Therefore, microbiome analysis around implant tissue was carried out to elucidate pathology of periimplantitis that caused by oral bacteria.
However, significant discovery that characterized bacterial composition and function of inflamed tissue around implant was not found in this study.

Report

(4 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Research-status Report
  • 2014 Research-status Report
  • Research Products

    (3 results)

All 2015

All Journal Article (2 results) (of which Peer Reviewed: 2 results,  Open Access: 1 results,  Acknowledgement Compliant: 1 results) Presentation (1 results)

  • [Journal Article] Screening of Pharmacologically Active Small Molecule Compounds Identifies Antifungal Agents Against Candida Biofilms.2015

    • Author(s)
      Watamoto T, Egusa H, Sawase T, Yatani H.
    • Journal Title

      Front Microbiol.

      Volume: 22 Pages: 1453-1453

    • DOI

      10.3389/fmicb.2015.01453

    • NAID

      120006987211

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Effect of Macroscopic Grooves on Bone Formation and Osteoblastic Differentiation.2015

    • Author(s)
      Miyahara K, Watamoto T, Uto Y, Sawase T.
    • Journal Title

      Implant Dent.

      Volume: 24(4) Pages: 370-376

    • DOI

      10.1097/id.0000000000000257

    • NAID

      120006986952

    • Related Report
      2015 Research-status Report
    • Peer Reviewed
  • [Presentation] インプラント周囲粘膜炎に対する音波式電動歯ブラシの効果2015

    • Author(s)
      里美香,加藤初美,綿本隆生,酒井桃子,澤瀬隆
    • Organizer
      日本口腔インプラント学会
    • Place of Presentation
      長崎市・長崎ブリックホール
    • Year and Date
      2015-01-31 – 2015-02-01
    • Related Report
      2014 Research-status Report

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Published: 2014-04-04   Modified: 2018-03-22  

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