| Budget Amount *help |
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2017: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2016: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2015: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2014: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
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| Outline of Final Research Achievements |
This study aimed at preparation of single crystal nanotube apatite and its application to biomaterials. A wet apatite synthesizer was used for the experiment. After heating ammonium phosphate and adjusting the pH with an ammonia solution, calcium acetate was added dropwise. In addition, hydrogen fluoride was added to the solution in order to enhance the crystallinity later in the synthesis experiment. It was immersed in lactic acid in order to open the pores of nanospace in the center of the synthesized crystal.
When the crystals after immersion were observed with a transmission electron microscope, a large number of rod-shaped apatites with holes in the center were observed. The c-axis cross section of the crystal is hexagonal and a sharp hole image is observed at the center of the crystal. The apatite was implanted in the rat's tooth extraction cavity, but no acceleration of healing was observed.
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