Analyzed stem cell differentiation and regeneration property treated by non steroidal anti-inflammatory agent
| Project/Area Number |
26462981
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Dental engineering/Regenerative dentistry
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| Research Institution | The Nippon Dental University |
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Principal Investigator |
Tsutsui Takeo 日本歯科大学, 生命歯学部, 教授 (70366764)
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| Co-Investigator(Kenkyū-buntansha) |
中原 貴 日本歯科大学, 生命歯学部, 教授 (10366768)
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| Project Period (FY) |
2014-04-01 – 2017-03-31
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| Project Status |
Completed (Fiscal Year 2016)
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| Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2016: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2015: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2014: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
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| Keywords | 歯髄幹細胞 / 歯根膜細胞 / 非ステロイド性抗炎症薬 / アスピリン / NSAIDs / 幹細胞 / 分化誘導 / 酸性非ステロイド性抗炎症薬 / 歯根膜幹細胞 |
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| Outline of Final Research Achievements |
We analyzed stem cell property that treated with non steroidal anti-inflammatory agent (NSAIDs) using mouse dental pulp cells, human dental pulp stem cells and human periodontal ligament cells. Differentiation potential analyzed by treated with high dose or low dose aspirin. Cultured in osteogenic and adipogenic differentiation medium, prompt positive staining reveled in treated with high dose aspirin. When cultured in adipogenic medium, prompt positive staining reveled in treated with high dose aspirin.
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Report
(4 results)
Research Products
(1 results)
