| Budget Amount *help |
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2016: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2015: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2014: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
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| Outline of Final Research Achievements |
In order to investigate the relationship between BRONJ occurrence risk and immune function, we first planned to create model mice with different BRONJ occurrence risk. The four model mice used in this study are planned to be prepared in accordance with the past method, and because there is some already established by research collaborators, we have matched the mouse with this study. We also plan to investigate the immune function of each mouse, 1) investigate the tissue localization of DC using immunohistochemical staining method, 2) stage to establish DC preparation method from peripheral blood .
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