Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2016: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2015: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2014: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
|
Outline of Final Research Achievements |
We found that the sentinel lymph node expression of VEGF-C, Foxp3, CD68 and CD163 are higher than non-sentinel lymph node. And the expression of PDL1 in primary tumor with metastatic lymph node patients was higher than non lymph node metastasis patients. And we examined sera derived from OSCC patients for multiple cytokines by using a multiplexed measurement system, and the results showed that the serum IL-6 and IL-8 level tended to negatively correlate with favorable outcome in these patients disease-free survival (DFS) was significantly longer in the Stage I/II OSCC patients with low serum IL-6/8 levels compared to those with high levels.
|