bone regneration technique wit non-cultured mono nuclear cell derived from peripheral blood
| Project/Area Number |
26463061
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (C)
|
| Allocation Type | Multi-year Fund |
|---|
| Section | 一般 |
|---|
| Research Field |
Surgical dentistry
|
|---|
| Research Institution | Nagasaki University |
|---|
Principal Investigator |
OHBA Seigo 長崎大学, 病院(歯学系), 講師 (80363456)
|
|---|
| Research Collaborator |
SANO Kazuo
ASAHINA Izumi
Blake Roessler J
|
|---|
| Project Period (FY) |
2014-04-01 – 2017-03-31
|
| Project Status |
Completed (Fiscal Year 2016)
|
| Budget Amount *help |
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2016: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2015: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2014: ¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
|
|---|
| Keywords | 骨再生 / PRP / hydroxyapatite/collagen / 単核球 / ReFit / bone regeneration / leptin |
|---|
| Outline of Final Research Achievements |
Bone regeneration was induced by hydroxyapatite/collagen composite material (HAp/Col) as a carrer and non-cultured total peripheral blood. HAp/Col with peripheral blood (PB group) or normal salin (NS group) were implanted on the calvarium of nude mice. The mature bone regeneration was observed 8 postoperative weeks in PB group. The volume of new bone was significantly much in PB group. In rabbits, HAp/col or HAp were filled into the maxillary sinus with peripheral blood. New bone was more induced in HAp/Col group same as mouse.
According to these results, HAp/Col with peripheral blood is considered to be useful for bone regeneration.
|
Report
(4 results)
Research Products
(11 results)
