| Budget Amount *help |
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2016: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2015: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2014: ¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
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| Outline of Final Research Achievements |
Bone regeneration was induced by hydroxyapatite/collagen composite material (HAp/Col) as a carrer and non-cultured total peripheral blood. HAp/Col with peripheral blood (PB group) or normal salin (NS group) were implanted on the calvarium of nude mice. The mature bone regeneration was observed 8 postoperative weeks in PB group. The volume of new bone was significantly much in PB group. In rabbits, HAp/col or HAp were filled into the maxillary sinus with peripheral blood. New bone was more induced in HAp/Col group same as mouse.
According to these results, HAp/Col with peripheral blood is considered to be useful for bone regeneration.
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