| Budget Amount *help |
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2016: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2015: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2014: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
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| Outline of Final Research Achievements |
We have previously demonstrated that muscle function MRI (mfMRI) and 31P-MRS are useful for assessing masseter fatigue. We attempted to establish a measurement method for masseter fatigue using the T2 relaxation time by mfMRI along with creatine phosphate (PCr) and inorganic phosphorus (Pi) by 31P-MRS in patients with mandibular protrusions as well as healthy subjects.
The average T2 time indicated a transient increase in both groups prior to and following experimental clenching. Moreover, the average T2 value of the patient group indicated a significant increase compared to that of the healthy group. PCr indicated a transient decreasing tendency in both groups with a tendency for fewer changes in the patient group compared to those in the healthy group. In addition, both groups indicated a transient Pi increasing tendency.
mfMRI and 31P-MRS are believed useful in assessing masseter fatigue in patients with mandibular protrusions.
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