Bacterial community of dental biofilm in children and its association with caries risk.
| Project/Area Number |
26463119
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Orthodontics/Pediatric dentistry
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| Research Institution | Tokyo Dental College |
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Principal Investigator |
Sakurai Atsuo 東京歯科大学, 歯学部, 講師 (90431759)
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| Co-Investigator(Kenkyū-buntansha) |
新谷 誠康 東京歯科大学, 歯学部, 教授 (90273698)
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| Co-Investigator(Renkei-kenkyūsha) |
HOMMA Hiromi 東京歯科大学, 歯学部, 助教 (80637760)
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| Project Period (FY) |
2014-04-01 – 2017-03-31
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| Project Status |
Completed (Fiscal Year 2016)
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| Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2016: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2015: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2014: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
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| Keywords | 口腔内細菌叢 / 齲蝕 / 口腔疾患 |
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| Outline of Final Research Achievements |
The dental biofilm is transparent or white in the early stages, but often becomes yellow or gray as it matures. Dental biofilm detected in children is white in most cases, but it is occasionally yellow or yellow-brown (colored biofilm). On the other hand, among children, there are also cases where dental caries and gingivitis are absent and oral health status is not poor despite the presence of colored biofilm. In the present study, the bacterial composition of colored biofilms from children was analyzed through 16s rRNA gene pyrosequencing. When the phylogenic tree was drawn, the distance between the colored and white biofilms was large in some cases, even for samples from the same subjects. Next, Relative abundance of each genus were compared between the colored and while biofilms. In children with severe ECC experiences, 6 genus were detected at significantly different frequencies between colored and white biofilms.
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Report
(4 results)
Research Products
(27 results)
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[Journal Article] 歯科大学病院小児歯科における初診患者の実態調査2014
Author(s)
岩田美奈子, 小鹿裕子, 浦野絢子, 荒井亮, 山頭亜里沙, 隝田みゆき, 辻野啓一郎, 櫻井敦朗, 大多和由美, 新谷誠康, 山下秀一郎
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Journal Title
小児歯科学雑誌
Volume: 52
Pages: 47-53
NAID
Related Report
Peer Reviewed / Acknowledgement Compliant
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[Journal Article] 歯科大学病院小児歯科における低年齢児齲蝕の実態調査2014
Author(s)
小鹿裕子, 岩田美奈子, 浦野絢子, 荒井亮, 山頭亜里沙, 隝田みゆき, 辻野啓一郎, 櫻井敦朗, 大多和由美, 新谷誠康, 山下秀一郎
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Journal Title
小児歯科学雑誌
Volume: 52
Pages: 54-61
NAID
Related Report
Peer Reviewed / Acknowledgement Compliant
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