| Project/Area Number |
26463140
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Periodontology
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| Research Institution | Kyushu Dental College |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
園木 一男 九州歯科大学, 歯学部, 准教授 (50316155)
吉野 賢一 九州歯科大学, 歯学部, 准教授 (90201029)
小田 昌史 九州歯科大学, 歯学部, 助教 (10638117)
田中 達朗 九州歯科大学, 歯学部, 准教授 (50326469)
守下 昌輝 九州歯科大学, 歯学部, 助教 (60710522)
中村 太志 九州歯科大学, 歯学部, 助教 (20549886)
森本 泰宏 九州歯科大学, 歯学部, 教授 (00275447)
中島 啓介 九州歯科大学, 歯学部, 教授 (80227785)
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| Project Period (FY) |
2014-04-01 – 2017-03-31
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| Project Status |
Completed (Fiscal Year 2016)
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| Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2016: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2015: ¥520,000 (Direct Cost: ¥400,000、Indirect Cost: ¥120,000)
Fiscal Year 2014: ¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
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| Keywords | 歯周基本治療 / fMRI / 血中レプチン / 脳 |
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| Outline of Final Research Achievements |
The aim of this study is to examine whether improvement of periodontal tissue affects changes in blood leptin and brain activity in chronic periodontitis patients. Periodontal initial treatment was showed significant improvement of periodontal tissue, and the activity of higher brain functions were confirmed in fMRI imaging. Chronic periodontitis was caused unpleasant irritation, and chronic periodontitis was inhibited work memory and higher brain function. However, periodontal initial treatment was removed unpleasant irritation and brain activation recovered.
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