| Budget Amount *help |
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2016: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2015: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2014: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
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| Outline of Final Research Achievements |
Saliva (SL), tongue coating (TC), supragingival plaque (AP), and subgingival plaque (BP) samples were collected twice from 14 patients with periodontitis who visited a dental clinic at their initial visit (pre-therapy samples) and after periodontal therapy (post-therapy samples). A principal coordinate analysis (PCoA) plot demonstrated that SL microbiota was distinct from both BP and AP microbiota, but closely similar to TC microbiota both pre- and post-therapy. Temporal variation following therapy in the SL and TC bacterial population was significantly smaller than in the AP microbiota, and relative abundances of the predominant bacterial species changed similarly in the SL and TC microbiota. These results suggested that the SL microbiota might originate from the TC microbiota.
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