Influence of change of tongue microbiota by smoking on oral malodor

• Project/Area Number: 26463175
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Social dentistry
• Research Institution: Fukuoka Dental College
• Principal Investigator: Taniguchi Nao 福岡歯科大学, 口腔歯学部, 准教授 (60372885)
• Co-Investigator(Kenkyū-buntansha): 廣藤 卓雄 福岡歯科大学, 口腔歯学部, 教授 (10189897) ; 中野 善夫 日本大学, 歯学部, 教授 (80253459)
• Project Period (FY): 2014-04-01 – 2019-03-31
• Project Status: Completed (Fiscal Year 2018)
• Budget Amount: ¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000); Fiscal Year 2016: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000); Fiscal Year 2015: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000); Fiscal Year 2014: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
• Keywords: 口臭 / 口腔内細菌 / 舌苔 / 喫煙 / 菌叢解析 / 揮発性硫黄化合物 / 細菌叢 / 16S rRNA / ブリンクマン指数 / ストレス / バイオマーカー

Outline of Final Research Achievements

Microbial compositions of saliva and tongue and immune system biomarkers in saliva were analyzed in 50 healthy adult volunteers (39 males, 11 females, average age 25.6 ± 2.1 years), and the differences of them between smokers and non-smokers were assessed. Four bacterial genera including Dialister, Atopobium, Treponema, and Selenomonas, which accounted for significantly higher rate in the oral cavity of smokers, have been reported as genera involved in periodontal diseases and oral malodor in the past studies. In addition, with regard to immune system biomarkers in saliva, IL-1beta was significantly higher in the smoking group than in the nonsmoking group, and a positive correlation between TNF-alpha and the Brinkman index was found.

Academic Significance and Societal Importance of the Research Achievements

喫煙は歯周病の最大の環境要因であるだけでなく、全身のさまざまな疾患の発症や進行に関係している。本研究の結果、臨床的に口腔および全身に問題がない若者において、既に菌叢や免疫システムが喫煙の影響を受けていることが明らかになり、十数年後に発症する歯周病や口臭、さらには全身疾患の基盤が構築されている可能性が示唆された。さらに、本研究で喫煙者において口臭関連細菌の割合が高いことが明らかになり、歯周病を介さない喫煙の口臭への直接的な関連が示唆された。

Research Products

• [Journal Article] Smoking and periodontal microorganisms. (2019)
  • Author(s): Hanioka T, Morita M, Yamamoto T, Inagaki K, Wang PL, Ito H, Morozumi T, Takeshita T, Suzuki N, Shigeishi H, Sugiyama M, Ohta K, Nagao T, Hanada N, Ojima M, Ogawa H.
  • Journal Title: JDSR Volume: -
  • NAID: 50014414225
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Induction and Inhibition of Oral Malodor. (2019)
  • Author(s): Suzuki N, Yoneda M, Takeshita T, Hirofuji T, Hanioka T.
  • Journal Title: Mol Oral Microbiol Volume: - Issue: 3 Pages: 85-96
  • DOI: 10.1111/omi.12259
  • Peer Reviewed / Open Access
• [Journal Article] Effects of Lactobacillus salivarius WB21 combined with green tea cathechins on dental caries. (2019)
  • Author(s): Higuchi T, Suzuki N, Nakaya S, Omagari S, Yoneda M, Hanioka T, Hirofuji T.
  • Journal Title: Arch Oral Biol Volume: 98 Pages: 243-247
  • DOI: 10.1016/j.archoralbio.2018.11.027
  • Peer Reviewed
• [Journal Article] Inhibition of protease activity of periodontopathogens by purified lactoferrin and lactoferrin supplements. (2019)
  • Author(s): Ishii A, Yoneda M, Matsuo T, Omagari S, Suzuki N, Yamamoto S, Morita H, Taniguchi Y, Koga C, Hirofuji T.
  • Journal Title: J Oral Hyg Health Volume: 7 Pages: 250-250
  • Peer Reviewed
• [Journal Article] Predicting oral malodour based on the microbiota in saliva samples using a deep learning approach (2018)
  • Author(s): Nakano Yoshio、Suzuki Nao、Kuwata Fumiyuki
  • Journal Title: BMC Oral Health Volume: 18 Issue: 1 Pages: 128-128
  • DOI: 10.1186/s12903-018-0591-6
  • Peer Reviewed / Open Access
• [Journal Article] Evaluation of a new ceramic-containing toothbrush bristle 1. Questionnaire survey on dental hygienist students about its usability and first impressions. (2018)
  • Author(s): Masahiro Yoneda, Ayako Ishii, Tadayuki Matsuo, Sami Omagari, Nao Suzuki, Takashi Tsuzuki, Yusuke Taniguchi, Hiromitsu Morita, Chihiro Koga, Yutaka Takahashi, and Takao Hirofuji.
  • Journal Title: J Oral Hyg Health Volume: 6 Issue: 02 Pages: 240-240
  • DOI: 10.4172/2332-0702.1000240
  • Peer Reviewed / Open Access
• [Journal Article] Porphyromonas gingivalis hydrogen sulfide enhances methyl mercaptan-induced pathogenicity in mouse abscess formation. (2018)
  • Author(s): Nakamura S, Shioya K, Hiraoka BY, Suzuki N, Hoshino T, Fujiwara T, Yoshinari N, Ansai T, Yoshida A.
  • Journal Title: Microbiology Volume: 164 Issue: 4 Pages: 529-539
  • DOI: 10.1099/mic.0.000640
  • Peer Reviewed
• [Journal Article] Association between secondhand smoke exposure and early eruption of deciduous teeth: A cross-sectional study (2018)
  • Author(s): Hanioka T, Ojima M, Tanaka K, Taniguchi N, Shimada K, Watanabe T.
  • Journal Title: Tobacco Induced Diseases Volume: 16:4 Issue: February Pages: 1-9
  • DOI: 10.18332/tid/84892
  • Peer Reviewed / Open Access
• [Journal Article] Two mechanisms of oral malodor inhibition by zinc ions. (2018)
  • Author(s): Suzuki N, Nakano Y, Watanabe T, Yoneda M, Hirofuji T, Hanioka T.
  • Journal Title: J Appl Oral Sci Volume: 26
  • Peer Reviewed
• [Journal Article] Integrating tobacco interventions into oral health program - Pilot implementation of the WHO brief tobacco intervention program in Japan. (2017)
  • Author(s): Hanioka T, Taniguchi N, Ojima M, Ogawa H.
  • Journal Title: Int J Oral Health Volume: 13 Pages: 32-40
  • Peer Reviewed
• [Journal Article] Probiotic Lactobacillus salivarius WB21 tablets on oral malodor among patients attending dental institution in Mysuru city, India-an open label pilot trial. (2017)
  • Author(s): Sharma P, Suzuki N, Chandrashekar BR, Thippeswamy HM, Hirofuji T, Tanabe K, Hanioka T, Avinash BS.
  • Journal Title: J Dent Oral Care Volume: 4 Pages: 1-8
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Relationship between salivary stress biomarker levels and cigarette smoking in healthy young adults: an exploratory analysis. (2016)
  • Author(s): Suzuki N, Nakanishi K, Yoneda M, Hirofuji T, Hanioka T.
  • Journal Title: Tobacco Induced Diseases Volume: 14 Issue: 1 Pages: 20-20
  • DOI: 10.1186/s12971-016-0085-8
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Resting salivary flow independently associated with oral malodor (2016)
  • Author(s): Nao Suzuki; Akie Fujimoto; Masahiro Yoneda; Takeshi Watanabe; Takao Hirofuji; Takashi Hanioka.
  • Journal Title: BMC Oral Health Volume: - Issue: 1 Pages: 23-23
  • DOI: 10.1186/s12903-016-0255-3
  • Peer Reviewed / Open Access
• [Journal Article] Inhibitory effect of Enterococcus faecium WB2000 on volatile sulfur compound production by Porphyromonas gingivalis. (2016)
  • Author(s): Suzuki N, Higuchi T, Nakajima M, Fujimoto A, Morita H, Yoneda M, Hanioka T, Hirofuji T.
  • Journal Title: International Journal of Dentistry Volume: 2016 Pages: 8241681-8241681
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] A case of oral malodor: improving the motivation of patients by use of bacterial examination. (2016)
  • Author(s): Yoneda M, Suzuki N, Fujimoto A, Ishii A, Yamada K, Masuo Y, Iwamoto T, Haraga M, Koga C, Morita H, Inoue Y, Hirofuji T.
  • Journal Title: Journal of Oral Hygiene & Health Volume: 4 Pages: 2-2
  • Peer Reviewed
• [Journal Article] Awareness and knowledge of halitosis: Comparison of two grades of dental hygienist students. (2016)
  • Author(s): Inoue E, Yoneda M, Suzuki N, Matsuo T, Ishii A, Haraga M, Hirahashi K, Morita H, Koga C, Inoue Y, Yasukouchi H, and Hirofuji T.
  • Journal Title: J Oral Hyg Health Volume: - Issue: 05 Pages: 5-5
  • DOI: 10.4172/2332-0702.1000211
  • Peer Reviewed / Open Access
• [Journal Article] Consciousness and Knowledge of Nursing Home Workers About Oral (2016)
  • Author(s): Ishii A, Yoneda M, Suzuki N, Haraga M, Yamada K, Morita H, Hirahashi K, Koga C, Inoue Y and Hirofuji T.
  • Journal Title: J Oral Hyg Health Volume: - Issue: 05 Pages: 5-5
  • DOI: 10.4172/2332-0702.1000207
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] 口腔疾患の予防管理における乳酸菌の役割 (2016)
  • Author(s): 谷口奈央
  • Journal Title: 福岡歯科大学学会雑誌 Volume: 42 Pages: 47-52
• [Journal Article] Oral bacteria and bowel diseases-mini review. (2016)
  • Author(s): Yoneda M, Suzuki N, Morita H, Hirofuji T.
  • Journal Title: Journal of Gastrointestinal & Digestive System Volume: 6 Pages: 404-404
• [Journal Article] Halitosis patients at a newly established satellite dental hospital: analysis of patients and the role of dental hygienists. (2015)
  • Author(s): Yoneda M, Yamada M, Suzuki N, Uemura R, Fujimoto A, Fukuchi H, Morita H, Yamada K, Matsuo T, Ishii A, Koga C, Hirofuji T.
  • Journal Title: International Journal of Clinical Preventive Dentistry Volume: 11 Pages: 7-14
  • Peer Reviewed
• [Journal Article] Persistent oral malodor associated with periodontitis caused by tooth perforation. (2015)
  • Author(s): Yoneda M, Suzuki N, Fujimoto A, Morita H, Uemura R, Koga C, Hirofuji T.
  • Journal Title: Aperito Journal of Oral Health and Dentistry Volume: 1 Pages: 102-102
  • Peer Reviewed
• [Journal Article] Acceptance to receive dental treatment performed by students-Comparison of two dental hospitals of Fukuoka Dental College- (2015)
  • Author(s): Yoneda M, Suzuki N, Fujimoto A, Masuo Y, Yamada K, Morita H, Koga C, Hirofuji T.
  • Journal Title: International Journal of Clinical Preventive Dentistry Volume: 11 Pages: 67-72
  • Peer Reviewed
• [Journal Article] 歯学部学生の喫煙習慣と心理的健康感との関連 (2015)
  • Author(s): 谷口奈央、仲西宏介、米田雅裕、埴岡 隆、廣藤卓雄
  • Journal Title: 口腔衛生会誌 Volume: 65 Pages: 422-425
  • NAID: 110010006664
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] A natural experiment for inferring casual association between smoking and tooth loss: a study of a workplace contemporary cohort. (2015)
  • Author(s): Hanioka T, Haresaku S, Suzuki N, Shimada K, Watanabe T, Ojima M, Fujie K, Watanabe M.
  • Journal Title: International Journal of Statistics in Medical Research Volume: 4 Pages: 331-336
  • Peer Reviewed / Open Access
• [Journal Article] Antibacterial effect of surface pre-reacted glass ionomer filler and eluate – mini review. (2015)
  • Author(s): Yoneda M, Suzuki N, Hirofuji T.
  • Journal Title: Pharm Anal Acta Volume: 6 Pages: 349-349
• [Journal Article] Current status of the techniques used for halitosis analysis. (2015)
  • Author(s): Yoneda M, Suzuki N, Hirofuji T.
  • Journal Title: Austin Chromatography Volume: 2 Pages: 1024-1024
• [Journal Article] Halitosis patients at a newly established satellite dental hospital: analysis of patients and the role of dental hygienists. (2015)
  • Author(s): Yoneda M, Yamada M, Suzuki N, Uemura R, Fujimoto A, Fukuchi H, Morita H, Yamada K, Matsuo T, Ishii A, Koga C, Hirofuji T
  • Journal Title: Int J Clin Prev Dent Volume: 印刷中
  • Peer Reviewed
• [Journal Article] Lactobacillus salivasius WB21-contianing tablets for the treatment of oral malodor: a double-blind, randomized, placebo-controlled crossover trial-reply to letter. (2015)
  • Author(s): Suzuki N, Yoneda M, Tanabe K, Fujimoto A, Iha K, Seno K, Yamada K, Iwamoto T, Masuo Y, Hrofuji T
  • Journal Title: Oral Surg Oral Med Oral Pathol Oral Radiol Volume: 118 Issue: 4 Pages: 506-506
  • DOI: 10.1016/j.oooo.2014.06.014
  • Peer Reviewed
• [Journal Article] Lactobacillus salivarius WB21-containing tablets for the treatment of oral malodor: a double-blind, randomized, placebo-controlled crossover trial. (2014)
  • Author(s): Suzuki N, Yoneda M, Tanabe K, Fujimoto A, Iha K, Seno K, Yamada K, Iwamoto T, Masuo Y, Hirofuji T
  • Journal Title: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology Volume: 117 Issue: 4 Pages: 462-470
  • DOI: 10.1016/j.oooo.2013.12.400
  • Peer Reviewed / Open Access
• [Journal Article] Effects of Lactobacillus salivarius-containing tablets on caries risk factors: a randomized open-label clinical trial. (2014)
  • Author(s): Nishihara T, Suzuki N, Yoneda M, Hirofuji T
  • Journal Title: BMC Oral Health Volume: 14 Issue: 1 Pages: 110-110
  • DOI: 10.1186/1472-6831-14-110
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Effects of S-PRG eluate on oral biofilm and oral malodor. (2014)
  • Author(s): Suzuki N, Yoneda M, Haruna K, Masuo Y, Nishihara T, Nakanishi K, Yamada K, Fujimoto A, Hirofuji T.
  • Journal Title: Archives of Oral Biology Volume: 59 Issue: 4 Pages: 407-413
  • DOI: 10.1016/j.archoralbio.2014.01.009
  • Peer Reviewed / Open Access
• [Journal Article] The detection of Candida species in patients with halitosis. (2014)
  • Author(s): Koga C, Yoneda M, Nakayama K, Yokoue S, Haraga M, Oie T, Suga A, Okada F, Matsuura H, Tsue F, Suzuki N, Hirofuji T
  • Journal Title: Int J Dent Volume: なし Pages: 857647-857647
  • DOI: 10.1155/2014/857647
  • Peer Reviewed / Open Access
• [Journal Article] Supervised machine learning-based classification of oral malodor based on the microbiota in saliva samples. (2014)
  • Author(s): Nakano Y, Takeshita T, Kamio N, Shiota S, Shibata Y, Suzuki N, Yoneda M, Hirofuji T, Yamashita Y.
  • Journal Title: Artificial Intelligence in Medicine Volume: 60 Issue: 2 Pages: 97-101
  • DOI: 10.1016/j.artmed.2013.12.001
  • Peer Reviewed / Open Access
• [Journal Article] 口臭除去を効能とする口腔咽喉薬 (トローチ剤) の臨床的評価 (2014)
  • Author(s): 仲西宏介、鈴木奈央、米田雅裕、山田潤一、廣藤卓雄
  • Journal Title: 日歯保存誌 Volume: 57 Pages: 293-300
  • NAID: 130004687185
  • Peer Reviewed
• [Presentation] 乳酸菌配合タブレットの継続摂取が健康な高齢者の口腔の健康維持に与える影響 (2018)
  • Author(s): 谷口奈央、廣藤卓雄、埴岡 隆、田邊一成
  • Organizer: 九州口腔衛生学会
• [Presentation] WHO推奨歯科簡易タバコ介入の日本版e-learningの開発 (2018)
  • Author(s): 埴岡 隆、谷口奈央、渡辺 猛、島津 篤、内藤麻利江、高江洲 雄、小島美樹、小川祐司
  • Organizer: 九州口腔衛生学会
• [Presentation] 歯周基本治療における乳酸菌配合タブレットの継続摂取の影響についての細菌学的検討 (2018)
  • Author(s): 谷口奈央、太田純明、中野善夫、埴岡 隆
  • Organizer: 歯科基礎医学会
• [Presentation] 口臭症患者のNBM聴取: 大学病院の取り組み、シンポジウム「患者心理と口臭を理解するには」 (2018)
  • Author(s): 谷口奈央
  • Organizer: 日本口臭学会
  • Invited
• [Presentation] 口臭からみる従業員の健康、シンポジウム「労働者の歯と口からみる健康経営」 (2018)
  • Author(s): 谷口奈央
  • Organizer: 日本産業衛生学会
  • Invited
• [Presentation] 口臭のリスク診断に有用な新しい唾液成分と口腔機能の検査項目の探索 (2018)
  • Author(s): 谷口奈央、藤本暁江、渡辺 猛、島津 篤、内藤麻利江、廣藤卓雄、埴岡 隆
  • Organizer: 日本口腔衛生学会
• [Presentation] 日本の歯科医療へのWHO簡易タバコ介入法の統合導入研修プログラム開発 (2018)
  • Author(s): 埴岡 隆、廣藤卓雄、谷口奈央、小島美樹、小川祐司
  • Organizer: 日本口腔衛生学会
• [Presentation] S-PRG溶出液が歯周病原性細菌の相互作用へおよぼす影響 (2018)
  • Author(s): 大曲紗生、米田雅裕、谷口奈央、藤本暁江、廣藤卓雄
  • Organizer: 日本歯科保存学会
• [Presentation] Suppression of periodontal bacterial interactions by pre-reacted glass ionomer filtrate. (2018)
  • Author(s): Omagari S, Yoneda M, Suzuki N, Fujimoto A, Morita H, Grenier D, Hirofuji T.
  • Organizer: IADR
  • Int'l Joint Research
• [Presentation] 喫煙が舌苔の細菌叢に与える影響 (2016)
  • Author(s): 谷口奈央、中野善夫、米田雅裕、森田浩光、藤本暁江、桑田文幸、廣藤卓雄、埴岡 隆
  • Organizer: 第7回日本口臭学会
  • Place of Presentation: 名古屋市
  • Year and Date: 2016-06-18
• [Presentation] Porphyromonas gingivalisの増殖及び揮発性硫黄化合物産生に対するEnterococcus faecium WB2000株の抑制作用 (2016)
  • Author(s): 樋口拓哉、谷口奈央、藤本暁江、米田雅裕、埴岡 隆、廣藤卓雄
  • Organizer: 第114回日本歯科保存学会
  • Place of Presentation: 栃木市
  • Year and Date: 2016-06-09
• [Presentation] 乳酸菌配合タブレットが口臭および口腔環境に与える影響～インドにおけるopen-label試験の報告～ (2016)
  • Author(s): 谷口奈央、田邊一成、埴岡 隆、廣藤卓雄
  • Organizer: 第65回日本口腔衛生学会総会
  • Place of Presentation: 東京都
  • Year and Date: 2016-05-27
• [Presentation] 健康な若者における喫煙者と非喫煙者との口腔内細菌構成の違い (2016)
  • Author(s): 谷口奈央、中野善夫、米田雅裕、廣藤卓雄、桑田文幸、埴岡 隆
  • Organizer: 日本細菌学会
  • Place of Presentation: 大阪市
  • Year and Date: 2016-03-23
• [Presentation] 喫煙が舌苔と唾液の細菌叢に与える影響 (2016)
  • Author(s): 谷口奈央、中野善夫、廣藤卓雄、埴岡 隆
  • Organizer: 第38回九州口腔衛生学会
  • Place of Presentation: 福岡市
• [Presentation] "口腔フローラと健康" 乳酸菌を利用した口腔の健康管理 (2016)
  • Author(s): 谷口奈央
  • Organizer: 第20回腸内細菌学会
  • Place of Presentation: 東京都
  • Invited
• [Presentation] 歯学部学生における喫煙者と非喫煙者の唾液および舌苔の細菌叢解析 (2015)
  • Author(s): 谷口奈央、中野善夫、米田雅裕、廣藤卓雄、桑田文幸、埴岡 隆
  • Organizer: 福岡歯科大学学会
  • Place of Presentation: 福岡市
  • Year and Date: 2015-12-13
• [Presentation] The relationship between salivary biomarkers and smoking in healthy young adults. (2015)
  • Author(s): Taniguchi N, Nakanishi K, Yoneda M, Morita H, Hanioka T, Hirofuji T
  • Organizer: 国際歯科研究学会日本部会総会
  • Place of Presentation: 福岡市
  • Year and Date: 2015-10-30
  • Int'l Joint Research
• [Presentation] 歯学部学生における喫煙者と非喫煙者の口腔内細菌叢の比較 (2015)
  • Author(s): 中野善夫、谷口奈央、米田雅裕、廣藤卓雄、桑田文幸、埴岡 隆
  • Organizer: 歯科基礎医学会
  • Place of Presentation: 新潟市
  • Year and Date: 2015-09-11
• [Presentation] 口臭治療における舌苔の意義 (2015)
  • Author(s): 谷口奈央
  • Organizer: 日本口臭学会
  • Place of Presentation: 新潟市
  • Year and Date: 2015-07-04
  • Invited
• [Presentation] 唾液分泌量と口腔粘膜水分量が口臭に与える影響 (2015)
  • Author(s): 藤本暁江、谷口奈央、米田雅裕、森田浩光、廣藤卓雄、埴岡 隆
  • Organizer: 日本口臭学会
  • Place of Presentation: 新潟市
  • Year and Date: 2015-07-04
• [Presentation] 唾液マーカーを用いたストレスと喫煙の関連性についての研究 (2015)
  • Author(s): 仲西宏介、谷口奈央、米田雅裕、桝尾陽介、藤本暁江、萩尾佳那子、埴岡 隆、廣藤卓雄
  • Organizer: 日本歯科保存学会
  • Place of Presentation: 北九州市
  • Year and Date: 2015-06-25
• [Presentation] 喫煙習慣とストレスとの関連性 (2015)
  • Author(s): 谷口奈央、仲西宏介、米田雅裕、廣藤卓雄
  • Organizer: 日本口腔衛生学会
  • Place of Presentation: つくば市
  • Year and Date: 2015-05-17
• [Presentation] 塩化亜鉛洗口によるヒト口腔内細菌叢の変化と持続性 (2015)
  • Author(s): 鈴木奈央、中野善夫、米田雅裕、廣藤卓雄
  • Organizer: 日本細菌学会
  • Place of Presentation: 岐阜市
  • Year and Date: 2015-03-26 – 2015-03-28
• [Presentation] Antibiofilm activity of surface pre-reacted glass ionomer (S-PRG) filler. (2015)
  • Author(s): Fujimoto A, Yoneda M, Suzuki N, Masuo Y, Morita H, Oie T, Koga C, Hirofuji T
  • Organizer: 93rd General Session & Exhibition of the IADR
  • Place of Presentation: Boston
  • Year and Date: 2015-03-11 – 2015-03-14
• [Presentation] 大学生の喫煙とライフスタイル・ストレスとの関連性 (2014)
  • Author(s): 桝尾陽介、谷口奈央、福地浩文、藤本暁江、伊波幸作、萩尾佳那子、米田雅裕、廣藤卓雄
  • Organizer: 第41回福岡歯科大学学会総会
  • Place of Presentation: 福岡市
  • Year and Date: 2014-12-14
• [Presentation] 歯学部6年生の喫煙実態と生活習慣・ストレスとの関連 (2014)
  • Author(s): 桝尾陽介、谷口奈央、福地浩文、藤本暁江、伊波幸作、萩尾佳那子、米田雅裕、廣藤卓雄
  • Organizer: 第7回日本総合歯科学会総会・学術大会
  • Place of Presentation: 大阪市
  • Year and Date: 2014-11-28 – 2014-11-30
• [Presentation] 福岡歯科大学学生の喫煙状況と生活習慣・ストレスとの関連 (2014)
  • Author(s): 安 忠大、谷口奈央、福地浩文、米田雅裕、桝尾陽介、廣藤卓雄
  • Organizer: 第141回日本歯科保存学会秋季学術大会
  • Place of Presentation: 山形市
  • Year and Date: 2014-10-30 – 2014-10-31
• [Presentation] ヒト口腔内細菌叢に対する亜鉛イオンの影響 (2014)
  • Author(s): 鈴木奈央、中野善夫、松尾忠行、米田雅裕、廣藤卓雄
  • Organizer: 第56回歯科基礎医学会学術大会・総会
  • Place of Presentation: 福岡市
  • Year and Date: 2014-09-25 – 2014-09-27
• [Presentation] 乳酸桿菌Lactobacillus salivarius配合タブレットがう蝕リスク因子に与える影響 (2014)
  • Author(s): 鈴木奈央、米田雅裕、田邊一成、廣藤卓雄
  • Organizer: 第63回日本口腔衛生学会総会
  • Place of Presentation: 熊本市
  • Year and Date: 2014-05-29 – 2014-05-31
• [Book] 「お口からはじめましょう からだの健康」 (2016)
  • Author(s): 編集 第23回日本歯科医学総会記念誌編集委員会
  • Total Pages: 57
  • Publisher: 医歯薬出版株式会社
• [Book] Emerging trends in oral health sciences and dentistry (2015)
  • Author(s): Suzuki N, Yoneda M, Hirofuji T
  • Total Pages: 840
  • Publisher: In Tech