Does obesity cause lymphedema?- Diversified approaches to adipose tissue and lymph vessels
| Project/Area Number |
26463215
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Fundamental nursing
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| Research Institution | Nagoya University |
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Principal Investigator |
Takeno Yukari 名古屋大学, 医学系研究科(保健), 助教 (20509088)
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| Co-Investigator(Kenkyū-buntansha) |
藤本 悦子 名古屋大学, 医学系研究科(保健), 教授 (00107947)
有田 広美 福井県立大学, 看護福祉学部, 教授 (30336599)
大島 千佳 名古屋大学, 医学系研究科(保健), 准教授 (30405063)
間脇 彩奈 名古屋大学, 医学系研究科(保健), 助教 (10533341)
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| Project Period (FY) |
2014-04-01 – 2017-03-31
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| Project Status |
Completed (Fiscal Year 2016)
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| Budget Amount *help |
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2016: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2015: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2014: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
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| Keywords | リンパ浮腫 / 肥満 / 糖尿病 / ラット / リンパ速度 / インドシアニングリーン / 免疫組織化学 / 続発性リンパ浮腫 / リンパ動態 / リンパ浮腫生活指導 / 複合的理学療法 / 蛍光リンパ管造影 |
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| Outline of Final Research Achievements |
The purpose of the present study was to explore the relationship between obesity and lymphedema and then develop lymphedema care and the management.
Animal experiment, using obese rats and diabetes rats, was employed in measurement of lymph velocity, excretion time of labeled interstitial fluid, and lymph vessels and adipose tissue were examined by immunohistochemical study. These finding suggest that interstitial fluid is more likely to accumulate in the obese body than normal. Moreover, the lower level of leptin hormone and the heavier weight in lymphedema rats could cause uninhibited appetite and further weight gain. Based on the findings, we plan to develop lymphedema management.
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Report
(4 results)
Research Products
(19 results)
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[Presentation] A follow-up study of collateral pathways established after lymphadenectomy in rats2015
Author(s)
Takeno, Y, nakanishi, K, Mawaki, A, Oshima, C, Arita, H, Fujimoto, E.
Organizer
25th World Congress of Lymphology
Place of Presentation
San Francisco, USA
Year and Date
2015-09-07
Related Report
Int'l Joint Research
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[Presentation] PATTTERN OF FLUID ACCUMULATION IN THE LYMPHEDEMATOUS ARM REVEALED BY MAGNETIC RESONANCE2015
Author(s)
FUJIMOTO,E, TANIHO, Y, MAWAKI, A, OSHIMA, C, NAKANISHI, K, TAKENO, Y.
Organizer
25th World Congress of Lymphology
Place of Presentation
San Francisco, USA
Year and Date
2015-09-07
Related Report
Int'l Joint Research
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