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Effect of enteral nutrition with eicosapentaenoic acids (EPA) for prevention pressure ulcers in patients with cerebral infarction

Research Project

Project/Area Number 26463355
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Clinical nursing
Research InstitutionJuntendo University

Principal Investigator

OGAWA Kaoru  順天堂大学, 保健看護学部, 教授 (50177127)

Co-Investigator(Kenkyū-buntansha) 黒川 佳子  順天堂大学, 保健看護学部, 助教 (20637102)
桑村 淳子  順天堂大学, 保健看護学部, 講師 (80615815)
山本 拓史  順天堂大学, 医学部, 先任准教授 (50255684)
Project Period (FY) 2014-04-01 – 2018-03-31
Project Status Completed (Fiscal Year 2017)
Budget Amount *help
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2016: ¥260,000 (Direct Cost: ¥200,000、Indirect Cost: ¥60,000)
Fiscal Year 2015: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2014: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Keywords褥瘡 / 予防 / エイコサペンタエン酸 / 栄養 / 炎症
Outline of Final Research Achievements

To explore the effect of eiconosapentaenoic acid (EPA) for the pressure ulcer formation and outcome of ill patients with cerebral infarction. A total 53 patients with cerebral infarction on critically neurological condition. All patients were randomly assigned to two groups either with EPA or without EPA control diets, delivered during a minimum of 4 days and monitored 14-days. Those who received the study experienced significant outcomes in terms of decreasing the incidence of new pressure ulcers. EPA contributed to prevent pressure ulcers in patients. The beneficial effect of the EPA was associated with a lower occurrence of new pressure ulcers on the clinically nutritional management of outcomes. Nutritional management using EPA could be a useful option for pressure ulcer prevention in patients who need long-term immobile bed rest in a supine position, as with cerebral infarction patients.

Report

(5 results)
  • 2017 Annual Research Report   Final Research Report ( PDF )
  • 2016 Research-status Report
  • 2015 Research-status Report
  • 2014 Research-status Report
  • Research Products

    (14 results)

All 2018 2017 2016 2015

All Journal Article (3 results) (of which Peer Reviewed: 3 results) Presentation (11 results) (of which Int'l Joint Research: 2 results)

  • [Journal Article] Effect of enteral nutrition with eiconosapentaenoic and gammalinolenic acids for preventing pressure ulcers in patients after neurosurgery2017

    • Author(s)
      Kaoru Ogawa, Yoshiko Kurokawa, Junko KUwamura, Mizuya Wtanabe, Takuji Yamamoto
    • Journal Title

      Juntendo Journal of Health Sciences and Nursing

      Volume: 5 Pages: 18-27

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Effect of enteral nutrition with eiconosapentaenoic and gamma-linolenic acids for preventing pressure ulcers in patients after neurosurgery2017

    • Author(s)
      Kaoru Ogawa, Yoshiko Kurokawa, Junko Kuwamura, Mizuya Watanabe, Takuji Yamamoto
    • Journal Title

      Juntendo Journal of Health Sciences and Nursing

      Volume: 5 Pages: 18-27

    • Related Report
      2016 Research-status Report
    • Peer Reviewed
  • [Journal Article] 脳梗塞患者の褥瘡予防における多価不飽和脂肪酸栄養投与の検討2015

    • Author(s)
      黒川佳子、小川薫、桑村淳子、山本拓史、徳川城治、杉本幸
    • Journal Title

      順天堂保健看護研究

      Volume: 3 Pages: 15-20

    • NAID

      40020415208

    • Related Report
      2015 Research-status Report 2014 Research-status Report
    • Peer Reviewed
  • [Presentation] 不飽和脂肪酸投与による脳血管障害患者の褥瘡予防効果2018

    • Author(s)
      小川薫、桑村淳子、黒川佳子、山本拓史
    • Organizer
      第33回日本静脈経腸栄養学会学術集会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 急性期から回復期へのシームレスな栄養療法2018

    • Author(s)
      山本拓史
    • Organizer
      第33回日本静脈経腸栄養学会学術集会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 医師から見た栄養士の役割についての意識調査2018

    • Author(s)
      桑村淳子
    • Organizer
      第33回日本静脈経腸栄養学会学術集会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 多価不飽和脂肪酸投与による脳血管障害患者の褥瘡予防効果2017

    • Author(s)
      小川薫、黒川佳子、桑村淳子、山本拓史
    • Organizer
      第32回日本静脈経腸栄養学会学術集会
    • Place of Presentation
      岡山シンフォニーホール(岡山市北区表町1-5-1)
    • Year and Date
      2017-02-23
    • Related Report
      2016 Research-status Report
  • [Presentation] 非糖尿病患者における脳卒中急性期の経管経腸栄養の血糖値に及ぼす影響と低GI低GL製剤の効果について2017

    • Author(s)
      山本拓史、小川薫、浅田祐香子、高山卓也
    • Organizer
      第32回日本静脈経腸栄養学会学術集会
    • Place of Presentation
      岡山シンフォニーホール(岡山市北区表町1-5-1)
    • Year and Date
      2017-02-23
    • Related Report
      2016 Research-status Report
  • [Presentation] 在胎26週の超早産で超低出生体重児5人における皮膚トラブルとその関連要因の検討2017

    • Author(s)
      桑村淳子、小川薫
    • Organizer
      第32回日本静脈経腸栄養学会学術集会
    • Place of Presentation
      岡山シンフォニーホール(岡山市北区表町1-5-1)
    • Year and Date
      2017-02-23
    • Related Report
      2016 Research-status Report
  • [Presentation] Effect of enteral nutrition with eiconosapentaenoic and gammalinolenic acids for preventing pressure ulcers in patients with cerebral infarction2017

    • Author(s)
      Kaoru Ogawa, Yoshiko Kurokawa, Junko KUwamura, Mizuya Wtanabe, Takuji Yamamoto
    • Organizer
      39th Congress of European Society of Parenteral and Enteral Nutrition
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Effect of enteral nutrition with eiconosapentaenoic and gamma-linolenic acids for preventing pressure ulcers in patients after neurosurgery2016

    • Author(s)
      Kaoru Ogawa, Yoshiko Kurokawa, Junko Kuwamura, Mizuya Watanabe, Takuji Yamamoto
    • Organizer
      38th Congress of European Society of Parenteral and Enteral Nutrition
    • Place of Presentation
      Bella Center, Copenhagen, Denmark
    • Year and Date
      2016-09-17
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research
  • [Presentation] 超早産で超低出生体重児を受けもつ看護師のケア時における皮膚接触圧の検討2015

    • Author(s)
      桑村淳子、小川薫
    • Organizer
      日本看護科学学会第35回学術集会
    • Place of Presentation
      広島国際会議場(広島市中区中島町1-5)
    • Year and Date
      2015-12-05
    • Related Report
      2015 Research-status Report
  • [Presentation] 脳血管疾患患者の褥瘡予防における多価不飽和脂肪酸投与の効果検討2015

    • Author(s)
      黒川佳子、小川薫、桑村淳子、山本拓史、徳川城治、杉本幸
    • Organizer
      日本老年看護学会第20回学術集会
    • Place of Presentation
      パシフィコ横浜(横浜市西区みなとみらい1-1-1)
    • Year and Date
      2015-06-12 – 2015-06-13
    • Related Report
      2014 Research-status Report
  • [Presentation] 脳梗塞患者の褥瘡予防における多価不飽和脂肪酸栄養投与の検討2015

    • Author(s)
      黒川佳子、小川薫、桑村淳子、山本拓史、徳川城治、杉本幸
    • Organizer
      日本老年看護学会第20回学術集会
    • Place of Presentation
      パシフィコ横浜(横浜市西区みなとみらい1-1-1)
    • Year and Date
      2015-06-12
    • Related Report
      2015 Research-status Report

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Published: 2014-04-04   Modified: 2019-03-29  

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