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Development and evaluation a maternal and neonatal care system for prevention of group B Streptococcus disease

Research Project

Project/Area Number 26463420
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Lifelong developmental nursing
Research InstitutionNagoya City University

Principal Investigator

WAKIMOTO HIROKO  名古屋市立大学, 大学院看護学研究科, 准教授 (40336706)

Co-Investigator(Kenkyū-buntansha) 矢野 久子  名古屋市立大学, 看護学部, 教授 (00230285)
長谷川 忠男  名古屋市立大学, 大学院医学研究科, 教授 (10314014)
佐藤 剛  名古屋市立大学, 大学院医学研究科, 講師 (80326149)
Research Collaborator SUZUKI satoshi  
WAKIMOTO yukio  
Project Period (FY) 2014-04-01 – 2019-03-31
Project Status Completed (Fiscal Year 2018)
Budget Amount *help
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2016: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2015: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2014: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Keywords母子感染 / 母子感染予防 / GBS / 新生児 / 血清型 / 薬剤感受性 / CovR/S / 面接調査 / 看護学 / 感染症 / 細菌
Outline of Final Research Achievements

The subjects were children who developed early-onset GBS disease (EOGBSD) or late-onset GBS disease (LOGBSD) and their mothers from 5 institutes between 2007 and 2016. There were 14 cases of EOGBSD and 17 cases of LOGBSD, inborn cases were 4 cases both EOGBSD and LOGBSD, with estimated incidence of 0.10 per 1,000 live births for both EOGBSD and LOGBSD. We divided the study period into two parts; the period before (period I: 2007-2008) and after (period II: 2009-2016) issue of the guideline for prevention of vertical transmission in Japan. The incidence of EOGBS was significantly lower in period II (0.03 per 1,000 births) than in period I (0.42 per 1,000 births) (p = 0.02). The incidence of EOGBSD would further decline with proper timing of GBS screening, sampling site, culture method, and appropriate antibacterial prophylaxis for pregnant GBS carriers.

Academic Significance and Societal Importance of the Research Achievements

新生児側の要因と母側の要因と微生物側の要因を併せて解析し,新生児GBS感染症の発症要因を明らかにすることで,より良い周産期医療向上の一助となり,新生児GBS感染症の予防に寄与できると考える.GBS保菌妊産褥婦への必要なケアを明らかにし,ケアを講じることは,安心して子どもを産み育てることができ,周産期ケア向上の一助となる.

Report

(6 results)
  • 2018 Annual Research Report   Final Research Report ( PDF )
  • 2017 Research-status Report
  • 2016 Research-status Report
  • 2015 Research-status Report
  • 2014 Research-status Report
  • Research Products

    (8 results)

All 2018 2017 2016 2015 2014 Other

All Journal Article (1 results) (of which Peer Reviewed: 1 results,  Open Access: 1 results) Presentation (5 results) Book (1 results) Remarks (1 results)

  • [Journal Article] 早発型・遅発型B群レンサ球菌感染症の発症状況―多施設共同研究2007年~2016年―2018

    • Author(s)
      脇本寛子,矢野久子,大城誠,田中太平,松原康策,鈴木千鶴子,佐藤剛,今峰浩貴,垣田博樹,後藤盾信,杉浦時雄,加藤丈典,齋藤伸治,村松幹司,鈴木悟
    • Journal Title

      日本周産期・新生児医学会雑誌

      Volume: 54 Pages: 118-124

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access
  • [Presentation] GBS保菌妊産褥婦へのケアの現状と課題(第二報)―GBS保菌褥婦が疑問,不安,心配に思っていること―2018

    • Author(s)
      脇本寛子,矢野久子
    • Organizer
      第38回日本看護科学学会
    • Related Report
      2018 Annual Research Report
  • [Presentation] 早発型・遅発型GBS感染症発症児由来GBSの薬剤感受性と血清型(2012年~2015年,中間報告)2017

    • Author(s)
      脇本寛子,矢野久子,畑七奈子,長谷川忠男
    • Organizer
      第91回日本感染症学会
    • Related Report
      2017 Research-status Report
  • [Presentation] GBS保菌妊産褥婦へのケアの現状と課題(第一報)―GBS保菌妊婦が疑問,不安,心配に思っていること―2017

    • Author(s)
      脇本寛子,矢野久子
    • Organizer
      第37回日本看護科学学会
    • Related Report
      2017 Research-status Report
  • [Presentation] 早発型・遅発型GBS感染症の発症状況(2012年~2014年中間報告)2016

    • Author(s)
      脇本寛子,矢野久子,長谷川忠男
    • Organizer
      第59回日本感染症学会中日本地方会学術集会
    • Place of Presentation
      沖縄コンベンションセンター,カルチャーリゾートフェストーネ(沖縄)
    • Year and Date
      2016-11-24
    • Related Report
      2016 Research-status Report
  • [Presentation] 新生児GBS感染症の発症要因の検討2014

    • Author(s)
      脇本寛子,矢野久子,長谷川忠男
    • Organizer
      第57回日本感染症学会中日本地方会学術集会
    • Place of Presentation
      岡山コンベンションセンター(岡山)
    • Year and Date
      2014-10-25
    • Related Report
      2014 Research-status Report
  • [Book] 看護実践のための根拠がわかる母性看護技術,第2版2015

    • Author(s)
      脇本寛子
    • Total Pages
      312
    • Publisher
      メヂカルフレンド社
    • Related Report
      2015 Research-status Report
  • [Remarks] 名古屋市立大学看護学部感染予防看護学ホームページ

    • URL

      http://nurs.med.nagoya-cu.ac.jp/kansen.dir/index.html

    • Related Report
      2018 Annual Research Report 2017 Research-status Report 2016 Research-status Report 2015 Research-status Report 2014 Research-status Report

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Published: 2014-04-04   Modified: 2020-03-30  

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