The effects of foods on epigenetic alterations in gastric carcinogenesis
| Project/Area Number |
26500004
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Integrated Nutrition Science
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| Research Institution | University of Fukui |
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Principal Investigator |
Suto Hiroyuki 福井大学, 学術研究院医学系部門, 客員准教授 (50345683)
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| Co-Investigator(Kenkyū-buntansha) |
中本 安成 福井大学, 学術研究院医学系部門, 教授 (40293352)
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| Project Period (FY) |
2014-04-01 – 2017-03-31
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| Project Status |
Completed (Fiscal Year 2016)
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| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2016: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2015: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2014: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Keywords | ヘリコバクター・ピロリ / 胃癌 / 胃炎 / 食品 |
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| Outline of Final Research Achievements |
The aim of this study was to analyze the molecular mechanism of foods in gastric mucosal inflammation and gastric carcinogenesis. The extent of inflammation of the group with 10% salt food tended to be more severe than those of the group with regular diet and the group with catechin in Helicobacter pylori infection groups. However, no significant difference was recognized among these three groups in inflammatory cytokines and epigenetic alterations .
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Report
(4 results)
Research Products
(8 results)
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[Journal Article] A case of Helicobacter pylori-negative intramucosal well-differentiated gastric adenocarcinoma with intestinal phenotype.2015
Author(s)
Ozaki Y, Suto H, Nosaka T, Saito Y, Naito T, Takahashi K, Ofuji K, Matsuda H, Ohtani M, Hiramatsu K, Nemoto T, Imamura Y, Nakamoto Y.
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Journal Title
Clin J Gastroenterol
Volume: 8
Issue: 1
Pages: 18-21
DOI
Related Report
Peer Reviewed / Open Access
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[Presentation] Influence of antithrombotic drugs on gastric ulcer healing after endoscopic submucosal dissection.2016
Author(s)
Takahashi K, Suto H, Nosaka T, Saito Y, Ozaki Y, Hayama R, Naito T, Ofuji K, Matsuda H, Ohtani M, Hiramatsu K, Nemoto T, Nakamoto Y
Organizer
DDW2016
Place of Presentation
San Diego, America
Related Report
Int'l Joint Research
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