| Project/Area Number |
26540012
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Statistical science
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| Research Institution | Nagoya University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
松井 茂之 名古屋大学, 医学系研究科, 教授 (80305854)
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| Research Collaborator |
SHIMADZU Hideyasu 英国Laughborough大学, Department of Mathematical Sciences, 講師
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| Project Period (FY) |
2014-04-01 – 2017-03-31
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| Project Status |
Completed (Fiscal Year 2016)
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| Budget Amount *help |
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2016: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2015: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2014: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
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| Keywords | 空間疫学 / 薬剤疫学 / 副作用 / 自発報告 / 集積性 / 疾病集積性 / クラスタリング / シグナル検出 / 有害事象 / 集積性検出 |
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| Outline of Final Research Achievements |
We revealed similarities and differences between two publicly available database of spontaneous adverse event reports in drug uses - the Japanese Adverse Drug Event Report database and the US Food and Drug Administration Adverse Event Reporting System - and how they affect signal detection. Next, we applied a cluster detection test based on a scan statistic to a huge database of daily ambulance records of out-of-hospital cardiac arrest cases in Japan, and we could find the increased the daily incidence around every New Year’s Day. And, we performed some practical studies using databases effectively in pharmacoepidemiology, from the statistical viewpoints in spatial epidemiology and related fields.
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