| Budget Amount *help |
¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Fiscal Year 2016: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2015: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2014: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
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| Outline of Final Research Achievements |
High-throughput sequencing technology enables to determine various genomes for a same species. Given such a variety of genomes, it is more natural to consider all of such variations. However, majority of analysis method conducts mapping against only a single reference genome in first, which leads to loss of important information caused by mis-mapping. In order to capture individual data’s feature, we developed new approach to analyze NGS data by comparing two different NGS data sets directly and discovering sequence patterns which appears either of the two datasets and do not appear in the other. The proposed approach can be applied to various problems such as finding breakpoints in cancer genomes.
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